Results 71 to 80 of about 384,421 (314)

Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons   +31 more
wiley   +1 more source

The global burden of cardiovascular disease attributable to high alcohol use from 1990 to 2021: an analysis for the global burden of disease study 2021

open access: yesFrontiers in Public Health
BackgroundCardiovascular diseases (CVDs) are the leading global disease burden, with alcohol consumption closely linked to their occurrence. This study analyzes data from the Global Burden of Disease Study 2021 (GBD 2021) to assess the distribution and ...
Chaofeng Niu   +9 more
doaj   +1 more source

Estimation of years lived with disability due to noncommunicable diseases and injuries using a population-representative survey. [PDF]

open access: yesPLoS One, 2017
The Global Burden of Disease 2010 and the WHO Global Health Estimates of years lived with disability (YLDs) uses disability-weights obtained from lay health-state descriptions, which cannot fully reflect different disease manifestations, according to severity, treatment, and environment.
Park JI, Jung HH.
europepmc   +5 more sources

The changing of the guard: groupwork with people who have intellectual disabilities [PDF]

open access: yes, 2009
This paper considers the impact of service systems on group activities. It describes an inter-professional groupwork project facilitated by a social worker and a community nurse.
A. McClimens   +33 more
core   +1 more source

Immune‐Driven Expression in Inclusion Body Myositis With T‐Cell Large Granular Lymphocytic Leukemia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives T‐cell large granular lymphocytic leukemia (T‐LGLL), reported in up to 58% of inclusion body myositis (IBM) patients, is a rare leukemia of cytotoxic or less commonly helper T cells. The range of myopathies in T‐LGLL and the impact of coexisting T‐LGLL in IBM are not well understood. Our objectives are to investigate the spectrum of
Pannathat Soontrapa   +10 more
wiley   +1 more source

Patient outcomes up to 15 years after stroke: survival, disability, quality of life, cognition and mental health [PDF]

open access: yes, 2016
BACKGROUND: The global epidemiological shift of disease burden towards long-term conditions means understanding long-term outcomes of cardiovascular disease is increasingly important.
Bray, BD   +4 more
core  

Why do people lose their friends after a stroke? [PDF]

open access: yes, 2011
Background: It is well-known that people lose friends after a stroke; what is less well understood is why this occurs. Aims: This study explored why people lose contact with their friends, and whether there are any protective factors. It also examined
Angeleri   +32 more
core   +1 more source

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

The Global, Regional, and National Burden of Psoriasis: Results and Insights From the Global Burden of Disease 2019 Study

open access: yesFrontiers in Medicine, 2021
Background: Psoriasis is a common, chronic, inflammatory, debilitating, systemic disease with a great impact on healthcare systems worldwide. As targeted therapies have transformed the therapeutic landscape, updated estimates of the Global Burden of ...
Giovanni Damiani   +15 more
doaj   +1 more source

Estimasi Nilai Years Lived with Disability (YLD) Terhadap Penyakit Respirasi Akibat Rokok di Indonesia

open access: yesPharmaqueous: Jurnal Ilmiah Kefarmasian, 2021
Merokok merupakan salah satu kekhawatiran terbesar yang dihadapi dunia kesehatan karena menyebabkan lebih dari 5 juta orang meninggal dalam setahun. Penelitian ini bertujuan untuk mengetahui dampak rokok terhadap penyakit respirasi di Indonesia menggunakan Years Lived with Disability (YLD).
openaire   +2 more sources

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