Results 61 to 70 of about 66,680,146 (171)

The Serotonin 2B (5‐HT2B) Receptor: A Narrative Review of Preclinical and Clinical Evidence on the Safety Considerations and Therapeutic Potential for the Treatment of Depression

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 345-356, August 2026.
Major depressive disorder (MDD) and treatment‐resistant depression (TRD) remain leading causes of disability, providing the impetus for receptor‐level treatment strategies beyond monoamine reuptake. The serotonin 5‐HT2B receptor (5‐HT2BR) is uniquely positioned at the interface of central‐antidepressant mechanisms and peripheral cardiac risks.
Gia Han Le, Sabrina Wong, Danica E. Johnson, Diana K. Orsini, Yang Jing Zheng, Kayla M. Teopiz, Christine E. Dri, Joshua D. Rosenblat, Roger S. McIntyre   +8 more
wiley   +1 more source

Burden of cardiovascular disease deaths, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life years (DALYs) attributable to dietary risk factors in Australia, by age groups and sex between 1990 and 2019.

Burden of cardiovascular disease deaths, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life years (DALYs) attributable to dietary risk factors in Australia, by age groups and sex between 1990 and 2019.
George Siopis (15822194), Sheikh Mohammed Shariful Islam (6195494), Elena S. George (12595798), Rachel R. Huxley (12032179), Riaz Uddin (9715154), Sarah A. McNaughton (8622846), Ralph Maddison (39626), Sebastian V. Moreno (17803834), Katherine M. Livingstone (9735919)   +8 more
core   +1 more source

Global Dual Incidence‐Mortality Patterns of Prostate Cancer Across SDI Regions, 1990–2021: A Cross‐Sectional Study Based on Global Burden of Disease 2021

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background To facilitate the development of precision prevention and control measures, this research offers a comprehensive evaluation of the global prostate cancer landscape, with a specific focus on its incidence, mortality rates, and underlying risk factors.
Zhiping Ma, Cuicui Wang, Qin Zhang, Zhongyu Lu, Dongsheng Chen, Xing Zhang, Yan Wang   +6 more
wiley   +1 more source

Burden of major cardiovascular disease deaths, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life years (DALYs) attributable to dietary risk factors in Australia, by sex, in 1990 and 2019.

Burden of major cardiovascular disease deaths, years lived with disability (YLDs), years of life lost (YLLs), and disability-adjusted life years (DALYs) attributable to dietary risk factors in Australia, by sex, in 1990 and 2019.
George Siopis (15822194), Sheikh Mohammed Shariful Islam (6195494), Elena S. George (12595798), Rachel R. Huxley (12032179), Riaz Uddin (9715154), Sarah A. McNaughton (8622846), Ralph Maddison (39626), Sebastian V. Moreno (17803834), Katherine M. Livingstone (9735919)   +8 more
core   +1 more source

Global regional and national burden of cataract attributable to high body mass index from 1990 to 2019

BMJ Open
Objectives In order to estimate long-term trends of the years lived with disability (YLDs) for cataract due to high body mass index (BMI).Design and participants Data were retrieved from the Global Burden of Disease (GBD) 2019.
Xiaowen Lan, Baodong Zhang, Yuxi Ding
doaj   +1 more source

Ischemic Heart Disease in the Middle East and North Africa, 1990–2021: An Integrated Analysis of Temporal Trends, Country‐Level Variation, SDI Patterns, and Risk Factors

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Ischemic heart disease (IHD) remains a leading cause of mortality and disability worldwide. Using Global Burden of Disease (GBD) 2021 estimates, this study provides an integrated assessment of IHD burden across the Middle East and North Africa (MENA) region from 1990 to 2021, highlighting temporal trends, inter‐country heterogeneity,
Nahid Karamzad, Saeid Safiri, Amir Ghaffari Jolfayi, Seyed Ehsan Mousavi, Fatemeh Amiri, Mohammad Rahmanian, Mark J. M. Sullman, Ali‐Asghar Kolahi   +7 more
wiley   +1 more source

Post school transition: the experiences of students with disability

, 2015
The transition from school is an important period. All young people should be supported throughout this time to access options which allow them to meaningfully participate and contribute to our society as adults. Many young people with disability however
Children with Disability Australia
core  

Sex-specific and socioeconomic disparities in the global burden of inflammatory bowel disease in 204 countries, 1990–2021: projections to 2050

Frontiers in Immunology
BackgroundInflammatory bowel disease (IBD) represents a growing global health challenge, necessitating a systematic evaluation of its epidemiological trends and sociodemographic disparities.MethodsUsing Global Burden of Disease 2021 data, we quantified ...
Qingtong Li, Yanqi Kou, Mingcheng Zhang, Mingcheng Zhang, Chunyi Wu, Rongfo Mi, Wantong Jiang, Yufei Cheng, Lei Ge, Ke Yang, Zhe Huang, Yuan Tian, Yuan Tian, Botao Luo, Botao Luo, Yanping Ha, Yanping Ha, Wanyi Yin, Wei Guo, Wenwei Zhu, Jun Liu, Shicai Ye, Yijie Weng, Jiayuan Wu, Yuping Yang   +24 more
doaj   +1 more source

Epidemiology of Type 2 Diabetes Mellitus in the Middle East and North Africa Region From 1990 to 2021

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Type 2 diabetes mellitus (T2DM) represents a major and rapidly growing public health challenge worldwide, particularly in regions undergoing rapid demographic and lifestyle transitions. The present study aimed to report the burden and trends associated with T2DM in the Middle East and North Africa (MENA) region from 1990 to
Nahid Karamzad, Mohammad Rahmanian, Reza Aletaha, Mark J. M. Sullman, Ali‐Asghar Kolahi, Fikrettin Şahin, Saeid Safiri   +6 more
wiley   +1 more source

Global, regional, and national pancreatitis burden and health inequality of pancreatitis from 1990 to 2019 with a prediction from 2020 to 2034

BMC Public Health
Background Pancreatitis is a digestive system disease that imposes a significant burden on society. However, there is a lack of comprehensive research on the incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs),
Yu Wen, Yuan Luo, Yunpeng Huang, Zijian Zhang, Li Xiong, Yongxiang Wang   +5 more
doaj   +1 more source