Results 81 to 90 of about 166,885,457 (298)

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Converging Extracellular Vesicle Research in all domains of life towards understanding their potential functional application : Proceedings of the COMBIVET & OH-BOOST Joint Conference 2023: 8-9th September 2023 [PDF]

, 2023
About the COMBIVET & OH-Boost Joint Conference 2023 This conference is jointly organised by the ERA Chair COMBIVET and OH- Boost Twinning Project of the Estonian University of Life Sciences in partnership with the University of Tartu (UT), University ...
Estonian University of Life Sciences
core   +1 more source

Years of life lost because of premature death due to intentional and unintentional accidents in Ghazvin province from 2004 till 2008

Social Determinants of Health, 2015
Background: Accidents are the second cause of death in Iran and one of the significant challenges in public health. They can affect people in all ages.
Nahid Jafari, Ali Akbarisari, Fereshteh Faghihi, Targol Omidvar, Saharnaz Nedjat, Kimia Rahmatian, Maryam Hosainzadeh Milany   +6 more
doaj   +1 more source

Trends of potential years of life lost due to main causes of deaths in urban and rural population in Poland, 2002–2011 [PDF]

, 2015
The aim of the study was to analyse the level and the trends of Potential Years of Life Lost due to main causes of deaths in Poland in 2002–2011, with consideration of place of residence, urban-rural.
Katarzyna Piotrowska, Szpak, A., Dominik Maślach, Krzyzak, M., Michalina Krzyżak, Andrzej Szpak, Skrodzka, M., Katarzyna Florczyk, Piotrowska, K., Andrzej Szpak, Alfred Owoc, Owoc, A., Michalina Krzyżak, Florczyk, K., Iwona Bojar, Martyna Skrodzka, Iwona Bojar, Bojar, I., Dominik Maślach, Katarzyna Florczyk, Maslak, D., Martyna Skrodzka, Katarzyna Piotrowska, Alfred Owoc   +23 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The persistence of very low correlations between NIH research funding and disease burdens

Public Health in Practice
Objectives: The degree to which the allocation of disease-specific research funding by the NIH is proportional to disease burden is an important question.
Ashley J.R. Carter, Milena Gevorkian
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Working years of life lost due to alcohol mortality. Ad hoc statistical release.

, 2020
The aim of this ad hoc statistical release is to quantify the burden alcohol puts on the working-age population in ...

core  

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

FEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn, Artur Osyczka, Marcin Sarewicz   +2 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source