Results 61 to 70 of about 1,400,643 (336)

Treatment with surfactants enables quantification of translational activity by O-propargyl-puromycin labelling in yeast

open access: yesBMC Microbiology, 2021
Background Translation is an important point of regulation in protein synthesis. However, there is a limited number of methods available to measure global translation activity in yeast. Recently, O-propargyl-puromycin (OPP) labelling has been established
Jennifer Staudacher   +2 more
doaj   +1 more source

Reductive Biotransformation of Ethyl Acetoacetate: A Comparative Studies using Free and Immobilized Whole Yeast Cells [PDF]

open access: yes, 2008
Bioreduction of ethyl acetoacetate with free and immobilized yeast whole cell was achieved by using water and sucrose combination. After detachment from immobilized beads under basic condition, the corresponding ethyl(S)-(+)-3-hydroxybutanoate was ...
Amit R. Kumbhar   +3 more
core   +1 more source

Editorial: Yeast cell aging and death [PDF]

open access: yes, 2018
A conspicuous amount of knowledge about the molecular biol- ogy of the cell has come from studies on yeast Saccharomyces cere- visiae, mostly because of its unrivaled qualities as a toolkit for molecular genetics study.
Cristina Mazzoni, Sergio Giannattasio
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Pharmacokinetics and Biodistribution of Zinc-Enriched Yeast in Rats

open access: yesThe Scientific World Journal, 2014
Zinc-enriched yeast (ZnY) and zinc sulfate (ZnSO4) are considered zinc (Zn) supplements currently available. The purpose of the investigation was to compare and evaluate pharmacokinetics and biodistribution of ZnY and ZnSO4 in rats.
Shuangqing Zhang   +6 more
doaj   +1 more source

Vaginal yeasts in the era of "over the counter" antifungals [PDF]

open access: yes, 2000
OBJECTIVE: To establish whether there has been any rise in the prevalence of non-albicans Candida species isolated from vaginal swabs since the introduction of “over the counter” antifungal treatments.
Ashbee, H.R.   +4 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

The protein kinase Cmk2 negatively regulates the calcium/calcineurin signalling pathway and expression of calcium pump genes PMR1 and PMC1 in budding yeast

open access: yesCell Communication and Signaling, 2019
Through a genome-wide screen we have identified calcium-tolerant deletion mutants for five genes in the budding yeast Saccharomyces cerevisiae. In addition to CNB1 and RCN1 that are known to play a role in the calcium signalling pathway, the protein ...
Huihui Xu   +3 more
doaj   +1 more source

Effect of live yeast on ruminal biohydrogenation. A preliminary in vitro approach [PDF]

open access: yes, 2009
Introduction : Ruminant dietary feed additives such as live yeasts are used on field because of their ability to induce a better diet utilisation. Even if studies on their mode of action are still going on, references are scarce about live yeast diet ...
Bayourthe, Corine   +4 more
core  

Home - About - Disclaimer - Privacy