Results 61 to 70 of about 188,871 (300)

Inducing Efficient Cross-priming Using Antigen-coated Yeast Particles [PDF]

Journal of Immunotherapy, 2008
Saccharomyces cerevisiae stimulates dendritic cells (DCs) and represents a promising candidate for cancer vaccine development. Effective cross-presentation of antigen delivered to DCs is necessary for successful induction of cellular immunity. Here, we present a yeast-based vaccine approach that is independent of yeast's ability to express the chosen ...
Shanshan W, Howland, Takemasa, Tsuji, Sacha, Gnjatic, Gerd, Ritter, Lloyd J, Old, Karl Dane, Wittrup   +5 more
openaire   +2 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Mitochondrial ribosome assembly in Neurospora. Structural analysis of mature and partially assembled ribosomal subunits by equilibrium centrifugation in CsCl gradients [PDF]

, 1982
In Neurospora, one protein associated with the mitochondrial small ribosomal subunit (S-5, Mr 52,000) is synthesized intramitochondrially and is assumed to be encoded by mtDNA.
Lambowitz, Alan M., LaPolla, Robert J.
core   +1 more source

Cellulose-coated emulsion micro-particles self-assemble with yeasts for cellulose bio-conversion

Scientific Reports
In the quest for alternative renewable energy sources, a new self-assembled hybrid configuration of cellulose-coated oil-in-water emulsion particles with yeast was formed. In this research, the addition of yeasts (S.
Ester Korkus Hamal, Gilad Alfassi, Margarita Antonenko, Dmitry M. Rein, Yachin Cohen   +4 more
doaj   +1 more source

Amyloidogenic Peptide Fragments Designed From Bacterial Collagen‐like Proteins Form Hydrogel

Advanced Functional Materials, EarlyView.
This study identified amyloidogenic sequence motifs in bacterial collagen‐like proteins and exploited these to design peptides that self‐assemble into β‐sheet fibers and form hydrogels. One hydrogel supported healthy fibroblast growth, showing promise for biocompatible materials. Our work demonstrates that bacterial sequences can be harnessed to create
Vamika Sagar, Xuen J Ng, Lukas Lechel, Ashish Chand Rajwar, Hendrik Bargel, Abhishek A. Jalan   +5 more
wiley   +1 more source

Biological measurement beyond the quantum limit

, 2012
Quantum noise places a fundamental limit on the per photon sensitivity attainable in optical measurements. This limit is of particular importance in biological measurements, where the optical power must be constrained to avoid damage to the specimen.
A Ashkin, A Crespi, B Yurke, Boris Hage, C Selhuber-Unkel, DE Chang, EJ Peterman, EN Senning, F Wolfgramm, G Brida, Hans-A. Bachor, I Chavez, IM Tolić-Nørrelykke, J Abadie, Jiri Janousek, Joachim Knittel, JT Finer, JW Tay, K McKenzie, KC Neuman, KC Neuman, LP McGuinness, M Buchanan, MA Taylor, MB Nasr, MI Kolobov, Michael A. Taylor, N Treps, R Demkowicz-Dobrzański, R Huang, S Yamada, T Franosch, T Nagata, TG Mason, V Giovannetti, Vincent Daria, Warwick P. Bowen, WJ Greenleaf   +37 more
core   +1 more source

Differential distribution of factors involved in pre-mRNA processing in the yeast cell nucleus [PDF]

, 1990
The yeast cell nucleus has previously been shown to be divided into two regions by a variety of microscopic approaches. We used antibodies specific for the 2,2,7-trimethylguanosine cap structure of small nuclear ribonucleic acids (snRNAs) and for a ...
Potashkin, J. A., Derby, R. J., Spector, D. L.   +2 more
core   +1 more source

Advances in Using Hansenula polymorpha as Chassis for Recombinant Protein Production

Frontiers in Bioengineering and Biotechnology, 2019
The methylotrophic yeast Hansenula polymorpha, known as a non-conventional yeast, is used for the last 30 years for the production of recombinant proteins, including enzymes, vaccines, and biopharmaceuticals.
João Heitor Colombelli Manfrão-Netto, Antônio Milton Vieira Gomes, Nádia Skorupa Parachin   +2 more
doaj   +1 more source

Nanodiamond Quantum Sensors for Probing Free Radical Biology

Advanced Functional Materials, EarlyView.
Free radicals play key roles in cellular signaling and disease but remain difficult to measure in living systems. Nanodiamonds (NDs) with nitrogen‐vacancy (NV) centers enable quantum sensing of local magnetic noise via T₁ relaxometry, providing nondestructive radical detection in living cells.
Qi Lu, Yingke Wu, Tanja Weil
wiley   +1 more source

A unified mechanism for intron and exon definition and back-splicing. [PDF]

, 2019
The molecular mechanisms of exon definition and back-splicing are fundamental unanswered questions in pre-mRNA splicing. Here we report cryo-electron microscopy structures of the yeast spliceosomal E complex assembled on introns, providing a view of the ...
Cui, Yanxiang, Das, Rhiju, Espinosa, Sara, Hansen, Kirk C, Hill, Ryan C, Issaian, Aaron, Kappel, Kalli, Li, Xueni, Liu, Shiheng, Shi, Shasha, Zhang, Lingdi, Zhao, Rui, Zhou, Z Hong   +12 more
core