Results 41 to 50 of about 188,871 (300)
Synthesis of Fatty Acids by Yeast Particles [PDF]
Journal of Bacteriology, 1966 Klein, Harold P. (Ames Research Center, Moffett Field, Calif.). Synthesis of fatty acids by yeast particles. J. Bacteriol. 92: 130–135. 1966.—When a mitochondria-free homogenate of Saccharomyces cerevisiae was centrifuged at 100,000 × g for 60 min, the ...
openaire +2 more sources
Yeast processing bodies and stress granules: self-assembly ribonucleoprotein particles
Microbial Cell Factories, 2011 Processing bodies (PBs) and stress granules (SGs) are two highly conserved cytoplasmic ribonucleoprotein foci that contain translationally repressed mRNAs together with proteins from the mRNA metabolism.
Díez Juana, Giménez-Barcons Mireia
doaj +1 more source
A 20S particle ubiquitous from yeast to human
Journal of Molecular Evolution, 1987 We have purified and characterized a particle sedimenting at 20S from the postribosomal fraction of yeast, wheat germ, Drosophila melanogaster tissue culture cells, chicken embryo fibroblasts, rabbit reticulocyte lysate, and HeLa cells. Most of the protein constituents of the 20S particle have molecular weights of 20-35 kd and differ between species ...
Arrigo, André-Patrick +3 more
openaire +4 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms [PDF]
, 2013 Peer reviewedPublisher ...
Dennis, Rowena J +5 more
core +2 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Targeting Nanodiamonds to the Nucleus in Yeast Cells
Nanomaterials, 2020 Nanodiamonds are widely used for drug delivery, labelling or nanoscale sensing. For all these applications it is highly beneficial to have control over the intracellular location of the particles.
Aryan Morita +7 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis [PDF]
, 2015 This work was supported by a Merit Scholarship from the Islamic Development Bank (to M.M.U.T.), The Agency for Science, Technology and Research, Singapore (A*STAR) (M.F.M.S), the Medical Research Council (MRC) [NIRG GO800203 and Research Grant MR/L002620/
Edwardson, J Michael +4 more
core +2 more sources