Results 41 to 50 of about 1,465,723 (294)

SysBioChalmers/yeast-GEM: yeast 8.1.2

, 2018
<ul> <li>New features: <ul> <li><code>saveYeastModel.m</code> now checks if the model is a valid SBML structure; if it isn't it will error (PR <a href="https://github.com/SysBioChalmers/yeast-GEM ...
Feiran Li, Hongzhong Lu, Thomas Pfau, Benjamín J. Sánchez, Eduard J. Kerkhoven   +4 more
core   +1 more source

Rapid regulation of protein activity in fission yeast [PDF]

, 2008
Background: The fission yeast Schizosaccharomyces pombe is widely-used as a model organism for the study of a broad range of eukaryotic cellular processes such as cell cycle, genome stability and cell morphology. Despite the availability of extensive set
Sharom, Jeffrey R., Boe, Cathrine A., Tyers, Michael D., Boye, Erik, Kearsey, Stephen, MacNeill, Stuart Andrew, Pai, Chen-Chun, Skjolberg, Henriette C., Grallert, Beata, Garcia, Ignacio, Sharom Jeffrey R, Skjølberg, Henriette C., Beáta Grallert, Bøe Cathrine A, Erik Boye, Garcia Ignacio, Skjølberg Henriette C, MacNeill, Stuart A., Boye Erik, Ignacio Garcia, Michael D Tyers, Cathrine A Bøe, MacNeill Stuart A, Stuart A MacNeill, Tyers Michael D, Bøe, Cathrine Arnason, Pai Chen-Chun, Stephen Kearsey, Grallert Beáta, Bøe, Cathrine A., Chen-Chun Pai, Kearsey Stephen, Henriette C Skjølberg, Jeffrey R Sharom, MacNeill, Stuart Andrew; id_orcid   +34 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Targeting Nanodiamonds to the Nucleus in Yeast Cells

Nanomaterials, 2020
Nanodiamonds are widely used for drug delivery, labelling or nanoscale sensing. For all these applications it is highly beneficial to have control over the intracellular location of the particles.
Aryan Morita, Thamir Hamoh, Alina Sigaeva, Neda Norouzi, Andreas Nagl, Kiran J. van der Laan, Emily P. P. Evans, Romana Schirhagl   +7 more
doaj   +1 more source

Production of biopharmaceutical proteins by yeast: Advances through metabolic engineering.

, 2013
Production of recombinant proteins for use as pharmaceuticals, so-called biopharmaceuticals, is a multi-billion dollar industry. Many different cell factories are used for the production of biopharmaceuticals, but the yeast Saccharomyces cerevisiae is an
Nielsen, Jens, Nielsen, Jens B, Nielsen, Jens B,   +2 more
core   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Performance of a micro-engineered ultrasonic particle manipulator

, 2004
An ultrasonic microfluidic particle manipulator has been modeled and its experimentally measured separation performance has been compared with the modeled results for 1 µm latex particles, and yeast particles in ...
Hill, M., Harris, N.R., Harris, NR, Beeby, SP, White, N.M., Harris, N R, Beeby, S P, Hill, M, Townsend, R., Townsend, R, Beeby, S.P., White, N M, White, NM   +12 more
core   +1 more source

Marine yeast isolation and industrial application [PDF]

, 2014
Over the last century, terrestrial yeasts have been widely used in various industries, such as baking, brewing, wine, bioethanol and pharmaceutical protein production. However, only little attention has been given to marine yeasts. Recent research showed
Tucker, Gregory A., Daw, Zakaria Yehia, Tucker, Gregory A, Zaky, Abdelrahman Saleh, Du, Chenyu   +4 more
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source