Establishment of a novel cynomolgus monkey model of hyperuricemia
We established a novel hyperuricemia model in cynomolgus monkeys (A) via oral administration of potassium oxonate, hydrochlorothiazide, and adenine mixed in fruits and vegetables. This model (B) targets uric acid synthesis and enzymatic degradation, and (C) regulates renal and intestinal excretion, thereby stably elevating serum uric acid and serving ...
Ji‐Wei Wang +12 more
wiley +1 more source
Fibril Structure of Desiccation‐Protective Tardigrade Protein CAHS‐8
We present the atomic structure of the fibril formed by an intrinsically disordered protein that has been shown to be responsible for remarkable environmental stress in tardigrades. X‐ray crystallography reveals a unique mechanism of fibril assembly whereby a single helix forms a stable, antiparallel coiled‐coil dimer, which then assembles into a ...
Anas Malki +6 more
wiley +2 more sources
Correction: Yeast Midas' touch: recent advances in the valorisation of methanol by yeasts. [PDF]
Mauri A, Tejada LG, Blank LM.
europepmc +1 more source
Acoustofluidic Patterning for Improved Microtissue Histology
Microtissue histology is widely used to characterize microtissue phenotype and morphology. However, conventional microtissue histology workflows are inefficient and time‐consuming. This work introduces a novel embedding technique that uses acoustofluidics to improve the efficiency of microtissue histology and reduce the time required for data analysis.
Dhananjay V. Deshmukh +13 more
wiley +1 more source
Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions
This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan +3 more
wiley +2 more sources
Beer Production With Umbu (Spondias tuberosa) Using Conventional and Nonconventional Yeast. [PDF]
Almeida DP +10 more
europepmc +1 more source
Micro/Nanorobot for Drug Delivery—A Review of Material Selections
This review explores material strategies for biomedical micro/nanorobots, emphasizing their roles in propulsion, navigation, drug delivery, and biodegradability. It highlights advancements in metallic, polymeric, and hybrid materials, while addressing clinical translation challenges such as toxicity, immune response, and manufacturability.
Xiaozhuo Wu, Bingyun Li, Malcolm Xing
wiley +1 more source
Yeast Species Associated with Industrial Cultures of the Marine Microalgae <i>Tisochrysis lutea</i>: Temperature Profiles and Auxin Production. [PDF]
Matos M +6 more
europepmc +1 more source
Editorial: Diversity, function, and application of microbes in the fermentation or production of traditional food. [PDF]
Dong W, Chen S, Hu Y.
europepmc +1 more source
Prevalence of <i>Malassezia pachydermatis</i> yeasts in clinical infections in dogs: A single-center retrospective study at the University Veterinary Hospital, Stara Zagora, Bulgaria (2019-2023). [PDF]
Dinkova V, Rusenova N.
europepmc +1 more source

