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Current Trends of Yellow Fever in Nigeria: Challenges and Prospects
Yellow fever is a viral infection caused by yellow fever virus and is spread by the bite of an infected female mosquito (Aedes and Haemogogus species).
Abdulkadir, B. +10 more
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Endemic and Emerging Arboviruses of Mosquitoes in Ecuador
Arboviruses are arthropod-borne viruses that include many viruses of public health concern found in Ecuador. Dengue virus, yellow fever virus and Zika virus are in the Flaviridae family (1), while chikungunya virus and Mayaro virus are in the ...
Rachel Sippy +3 more
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Intradermally administered yellow fever vaccine at reduced dose induces a protective immune response: a randomized controlled non-inferiority trial. [PDF]
Implementation of yellow fever vaccination is currently hampered by limited supply of vaccine. An alternative route of administration with reduced amounts of vaccine but without loss of vaccine efficacy would boost vaccination programmes.A randomized ...
Anna H Roukens +4 more
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Introduction: Since the end of 2014, Zika virus (ZIKV) infection has been rapidly spreading in Brazil. Methodology: To analyze the possible association of yellow fever vaccine with a protective effect against ZIKV-related microcephaly, the following ...
Luciano Pamplona de Góes Cavalcanti +5 more
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Mathematical modeling provides kinetic details of the human immune response to vaccination
With major advances in experimental techniques to track antigen-specific immune responses many basic questions on the kinetics of virus-specific immunity in humans remain unanswered.
Dustin eLe +2 more
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Risk of yellow fever virus transmission in the Asia-Pacific region
Yellow fever is absent from the Asia/Pacific region, despite presence of the mosquito vector. Here, the authors demonstrate that mosquitoes collected from field sites across the region are capable of transmitting yellow fever virus, indicating that ...
Lucy de Guilhem de Lataillade +8 more
doaj +1 more source
Heretofore, the most reliable way of measuring yellow fever virus antibody was to use the mouse neutralization (MN) test employing either suckling or weanling mice. Certain disadvantages (e.g., expense both of animals and of maintaining a mouse colony, allergic reactions of many laboratory workers, and the relatively long time, 21 days, before end ...
S, Spector, N M, Tauraso
openaire +2 more sources
Alphaviral Capsid Proteins Inhibit Stress Granule Assembly via Competitive RNA Binding With G3BP1
Stress granules exert antiviral functions. This study illustrates a conserved function of alphaviral capsid proteins in modulating stress granules. Oligomerization mediated by a helical motif coupled with a positively charged intrinsically disordered region (IDR) directly competes with G3BP1 for RNA binding, thereby disrupting G3BP1‐RNA liquid–liquid ...
Yun Zhang +10 more
wiley +1 more source
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu +9 more
wiley +1 more source
Introduction: Yellow fever virus causes systemic disease of the liver, kidneys, myocardium and hemorrhage, which are high incidence and mortality. Lycopene is one of the effective antioxidants used to prevent the growth of cancerous tumors.
Gholamreza Dadashi Oranj
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