Results 61 to 70 of about 1,515 (202)

Multi‐Omics and Machine Learning‐Uncovered FLT1‐Mediated Epithelial‐Endothelial Crosstalk in Cellular Senescence Driving Clear Cell Renal Cell Carcinoma Malignancy

The FASEB Journal, Volume 40, Issue 8, 30 April 2026.
This study integrates multi‐omics data and machine learning to reveal FLT1 as a central mediator of epithelial‐endothelial crosstalk in clear cell renal cell carcinoma (ccRCC). We demonstrate that FLT1‐associated signaling promotes a senescence‐enriched tumor microenvironment, driving malignant progression. Spatial and single‐cell analyses confirm FLT1
Mouyuan Sun, Huchao Mao, Yaxian Luo, Mei Yang, Zhixu He, Shuangyang Li, Zhichao Liu, Lianjie Peng, Quanjie Zhang, Jingyu Zhang, Yan Zhang   +10 more
wiley   +1 more source

The Role of Artificial Intelligence in Medication Management for Older Adults: A Systematic Review

AGING MEDICINE, Volume 9, Issue 2, Page 196-213, April 2026.
Artificial intelligence enhances medication management for older adults by improving adherence, personalizing treatment, and predicting risks. Despite benefits, challenges remain in usability, trust, ethics, and system integration. Successful adoption requires user‐centered design, ethical safeguards, and seamless healthcare integration to ensure safe,
Dipak Chandra Das, Moustaq Karim Khan Rony, Shovit Dutta, MD. Sami Al Zubair Zujbe, Tapan Bhattacharjee, Niloy Debnath, Shabbir Abdullah Maruf, Chowdhury Galib Mortuza, Farhana Rahman, Akash Das   +9 more
wiley   +1 more source

Civilizational Orientation of the Population of the United Krasnoyarsk Krai: 15 to 60 Years of Age Residents of Krasnoyarsk City [PDF]

, 2011
In this article we shed some light upon the development of the concept of civilizational orientation» and create the concept of analyzing the conception of the world (and thence - relationship to the world, and behavior) population of the united ...
Ilbeykina, Maria I., Ильбейкина, М.И.   +1 more
core  

Plio-Pleistocene evolution of water mass exchange and erosional input at the Atlantic-Arctic gateway [PDF]

, 2016
Water mass exchange between the Arctic Ocean and the Norwegian-Greenland Seas has played an important role for the Atlantic thermohaline circulation and Northern Hemisphere climate.
Frank, Martin, Haley, Brian A., Knies, Jochen, Teschner, Claudia   +3 more
core   +2 more sources

Notarial Institution and Notaries of the Yenisei Province from 1897 to 1917

Bylye Gody, 2019
В статье приведены исторические сведения о деятельности нотариальных контор и профессиональных нотариусов Енисейской губернии с января 1897 по февраль 1917 гг. Установлено, что система нотариата при Министерстве юстиции была введена в Сибири с 30-летним отсрочиванием согласно «Высочайше утвержденным Временным правилам о применении Судебных Уставов к ...
openaire   +3 more sources

Integrative Single‐Cell and Machine Learning Analysis Identifies an EMT‐Associated Prognostic Signature for Papillary Thyroid Cancer

Cancer Medicine, Volume 15, Issue 4, April 2026.
ABSTRACT Background Epithelial–mesenchymal transition (EMT) plays a critical role in tumor progression; however, the underlying molecular mechanisms of EMT in papillary thyroid carcinoma (PTC) remain incompletely understood. This study aimed to investigate EMT‐related mechanisms in PTC using an integrative approach combining single‐cell RNA sequencing ...
Tianfeng Xu, Ruonan Sun, Yujie Zhang, Xun Zheng   +3 more
wiley   +1 more source

Factors of the Evolution of the Guild of Merchants of the Yenisei Province (in the post-reform period)

Bylye Gody, 2017
В публикуемой статье исследуется влияние фискально-правового, экономического, демографического, природно-географического факторов на эволюцию гильдейского купечества Енисейской губернии в 1860-е гг. − начале ХХ вв. Изучив данные статистики, сведения сословно-личностного характера, архивные документы, авторы пришли к выводу, что влияние каждого фактора ...
openaire   +3 more sources

Un pequeño Oso de las Cavernas (Ursus rossicus) del Sur de Siberia, Rusia BARYSHNIKOV, G. [PDF]

, 2001
[Abstract] The skull, mandibles and cheek teeth of U. Rossicus from four localities of the South Siberia are examined. This species inhabited the steppe regions in early Middle and Late Pleistocene. By odontological characters it is more close to U.
Baryshnikov, G., Foronova, I.
core   +1 more source

Redating shuidonggou locality 1 and implications for the initial upper paleolithic in east asia [PDF]

, 2014
A review of recently published temporal data from Shuidonggou Locality 1 indicates that a 40-43 cal ka date for the inception of Initial Upper Paleolithic (IUP) blade-oriented technologies in East Asia is warranted.
Barton, L, Bettinger, RL, Gao, X, Morgan, C, Peng, F, Yi, M   +5 more
core   +1 more source

Historical Experience in Dealing with Epidemics in the Yenisei Province in the late XIX – early XX centuries

Bylye Gody, 2019
The article on the materials of the Yenisei province analyzes the model of interaction between the executive authorities, city government and public organizations in the fight against epidemics in the late XIX – early XX centuries. The main directions of anti-epidemic activities in the Yenisei Siberia are characterized, the legal and financial ...
Marinenko L.E, Kattsina T.A, Karabulatova, I. S., Mezit, L. E.   +3 more
openaire   +3 more sources