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Immunogenicity and Protective Efficacy of the First Autogenous Aeromonas hydrophila Vaccine for Piaractus brachypomus

Journal of Fish Diseases, EarlyView.
ABSTRACT Aeromonas hydrophila is a major zoonotic bacterial pathogen responsible for haemorrhagic septicemia, substantial economic losses in aquaculture and increasing antimicrobial resistance among field isolates. It is also one of the main bacterial species associated with mortality outbreaks in pirapitinga, Piaractus brachypomus, culture in the ...
Layana Aparecida Batista Pereira +7 more
wiley +1 more source

Development of a Multiplex Polymerase Chain Reaction Assay for Differentiating Three Lactococcus Species Associated With Piscine Lactococcosis

Journal of Fish Diseases, EarlyView.
ABSTRACT Piscine lactococcosis is an important bacterial disease of farmed fish. The causative agents, Lactococcus garvieae, Lactococcus petauri and Lactococcus formosensis, are closely related, which complicates species‐level identification. We developed a conventional multiplex PCR assay targeting species‐specific genes identified by comparative ...
Tomoaki Yoshino +9 more
wiley +1 more source

Development of a Multiplex Quantitative PCR Assay for Simultaneous Detection of Multiple Vibrio Species in Aquaculture Samples

Journal of Fish Diseases, EarlyView.
ABSTRACT Aquaculture associated Vibrio species are important bacterial pathogens causing significant economic losses in aquaculture and zoonotic infections in humans. Rapid and accurate detection of Vibrio species is therefore essential for diagnosis, surveillance and control.
İnci Başak Müştak +7 more
wiley +1 more source

Bacterial composition of Polygenis (Polygenis) bohlsi bohlsi (Wagner, 1901) (Siphonaptera: Rhopalopsyllidae) associated with Thrichomys fosteri (Rodentia: Echimyidae) in the Brazilian Pantanal wetland

Medical and Veterinary Entomology, EarlyView.
This study characterizes the bacteriome of Polygenis (Polygenis) bohlsi bohlsi fleas collected from free‐living Thrichomys fosteri in the Pantanal region of Brazil. The bacterial microbiota associated with male fleas exhibited greater phylogenetic diversity, and the overall community structure differed between the flea sexes.
Michelli Inácio Gonçalves Funnicelli +13 more
wiley +1 more source

A Genetic Risk Variant Associated With the Risk of Primary Biliary Cholangitis Is Inherited From Neanderthals

Liver International, Volume 46, Issue 10, October 2026.
ABSTRACT Background Primary Biliary Cholangitis (PBC) is an autoimmune cholangiopathy with polygenic architecture and unknown aetiology. Evidence links Neanderthal‐derived genetic variants to autoimmune conditions; however, their contribution to PBC susceptibility remains unexplored.
Alessio Gerussi +269 more
wiley +1 more source

Faecal Microbiota Transplantation Reduces Lesion Severity and Medication Use in Canine Atopic Dermatitis: A Randomised, Placebo‐Controlled, Double‐Blinded Clinical Trial

Veterinary Dermatology, Volume 37, Issue 5, Page 735-744, October 2026.
Background: Faecal microbiota transplantation (FMT) is an established therapy for gastrointestinal disease, yet its role in canine atopic dermatitis (cAD) remains unclear. Hypothesis/Objectives: We hypothesised that adjunctive FMT improves clinical severity and reduces symptomatic medication use in dogs with cAD.
Vera Felten +9 more
wiley +1 more source

Untersuchung von Anti‐Glykan‐Antikörpern und Erforschung ihres medizinischen Potenzials mithilfe synthetischer Glykane

Angewandte Chemie, Volume 138, Issue 39, 21 September 2026.
Anti‐Glykan‐Antikörper spielen sowohl bei Gesundheit als auch bei Krankheit eine wesentliche Rolle. Der Zugang zu neuartigen Glykanstrukturen ermöglicht Fortschritte bei der Antikörpercharakterisierung für die Entdeckung von Biomarkern, die Antikörperentwicklung und das Impfstoffdesign.
Fabienne Weber +4 more
wiley +1 more source

Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential

Angewandte Chemie International Edition, Volume 65, Issue 39, 21 September 2026.
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source

Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression

Biotechnology Journal, Volume 21, Issue 9, September 2026.
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Wian Vermeulen +2 more
wiley +1 more source

Unlocking the Multifunctional Properties of Litsea cubeba Essential Oil: Composition, Antimicrobial, Antibiofilm and Insecticidal Activities

Flavour and Fragrance Journal, Volume 41, Issue 5, Page 1201-1216, September 2026.
Unveiling the chemical and biological properties of Litsea cubeba essential oil. ABSTRACT Litsea cubeba essential oil (LCEO) is recognised for its broad spectrum of biological activities, including antimicrobial and insecticidal effects, making it a promising natural alternative to synthetic agents.
Miroslava Kačániová +10 more
wiley +1 more source