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Biochemical Society Transactions, 2003
Yersinia pestis is the aetiological agent of plague, a disease of humans that has potentially devastating consequences. Evidence indicates that Y. pestis evolved from Yersinia pseudotuberculosis, an enteric pathogen that normally causes a relatively mild disease. Although Y.
Richard W. Titball +3 more
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Yersinia pestis is the aetiological agent of plague, a disease of humans that has potentially devastating consequences. Evidence indicates that Y. pestis evolved from Yersinia pseudotuberculosis, an enteric pathogen that normally causes a relatively mild disease. Although Y.
Richard W. Titball +3 more
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Bacteriophages of Yersinia pestis
2016Bacteriophage play many varied roles in microbial ecology and evolution. This chapter collates a vast body of knowledge and expertise on Yersinia pestis phages, including the history of their isolation and classical methods for their isolation and identification. The genomic diversity of Y. pestis phage and bacteriophage islands in the Y. pestis genome
Mikael Skurnik, Xiangna Zhao
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Rational taxonomy of Yersinia pestis
Molecular Genetics Microbiology and Virology (Russian version), 2019Plague is a zoonotic infection whose pathogenic agent has caused hundreds of million human deaths. A broad range of hosts and vectors, along with the geographical dispersion of natural plague foci characterized by different ecological conditions, contribute to the formation of the polytypic Y.
Svetlana V. Dentovskaya +5 more
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Molecular typing of Yersinia pestis
Molecular Genetics, Microbiology and Virology, 2013Techniques for differentiating single bacterial isolates into intraspecies clusters corresponding to subspecies, biovars, and natural foci are reviewed. The techniques under consideration are reproducible under different laboratory settings. A version of the intraspecies classification of Y.
Svetlana V. Dentovskaya +3 more
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2016
This chapter summarized the taxonomy and typing works of Yersinia pestis since it's firstly identified in Hong Kong in 1894. Phenotyping methods that based on phenotypic characteristics, including biotyping, serotyping, antibiogram analysis, bacteriocin typing, phage typing, and plasmid typing, were firstly applied in classification of Y.
Qingwen Zhang +3 more
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This chapter summarized the taxonomy and typing works of Yersinia pestis since it's firstly identified in Hong Kong in 1894. Phenotyping methods that based on phenotypic characteristics, including biotyping, serotyping, antibiogram analysis, bacteriocin typing, phage typing, and plasmid typing, were firstly applied in classification of Y.
Qingwen Zhang +3 more
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Characterization of the lipopolysaccharide of Yersinia pestis
Microbial Pathogenesis, 2001Lipopolysaccharide (LPS) extracted from eight strains of Yersinia pestis, which had been cultured at 28 or 37 degrees C, reacted equally well, in Western blots, with four monoclonal antibodies generated against the LPS from a single strain of Y. pestis cultured at 28 degrees C. LPS was extracted and purified from Y.
Richard W. Titball +7 more
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Yersinia pestis (plague) vaccines
Expert Opinion on Biological Therapy, 2004Live attenuated and killed whole cell vaccines against disease caused by Yersinia pestis have been available since the early part of the last century. Although these vaccines indicate the feasibility of protecting against disease, they have a number of shortcomings. The live attenuated vaccine is highly reactogenic and is not licensed for use in humans.
E. Diane Williamson, Richard W. Titball
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Pathology and Pathogenesis of Yersinia pestis
2016Various types of animal models of plague have been developed, including mice, rats, guinea pigs, and nonhuman primates. Studies have indicated that rodent and nonhuman primate models of pneumonic plague closely resemble the human disease and that the pathologic changes that occur during bubonic plague are very similar in rodents, nonhuman primates, and
Zongmin Du, Xiaoyi Wang
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2002
Publisher Summary Bubonic plague caused by Yersinia pestis ranks as the most severe bacterial disease known to humanity. In the mouse, this bleak process consists of an initial invasive stage characterized by the colonization of the host viscera from the dermal sites of infection caused by fleabite.
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Publisher Summary Bubonic plague caused by Yersinia pestis ranks as the most severe bacterial disease known to humanity. In the mouse, this bleak process consists of an initial invasive stage characterized by the colonization of the host viscera from the dermal sites of infection caused by fleabite.
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2010
Bubonic plague is a flea-borne zoonosis caused by the Gram-negative bacterium Yersinia pestis, which mainly affects small burrowing mammals including domestic rats. Human disease occurs in endemic countries—currently mainly in Africa (including Madagascar)—following bites from fleas recently hosted by a bacteraemic animal.
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Bubonic plague is a flea-borne zoonosis caused by the Gram-negative bacterium Yersinia pestis, which mainly affects small burrowing mammals including domestic rats. Human disease occurs in endemic countries—currently mainly in Africa (including Madagascar)—following bites from fleas recently hosted by a bacteraemic animal.
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