Results 11 to 20 of about 20,709 (178)

Acquisition of yersinia murine toxin enabled Yersinia pestis to expand the range of mammalian hosts that sustain flea-borne plague.

PLoS Pathogens, 2021
Yersinia murine toxin (Ymt) is a phospholipase D encoded on a plasmid acquired by Yersinia pestis after its recent divergence from a Yersinia pseudotuberculosis progenitor. Despite its name, Ymt is not required for virulence but acts to enhance bacterial
David M Bland, Adélaïde Miarinjara, Christopher F Bosio, Jeanette Calarco, B Joseph Hinnebusch   +4 more
doaj   +1 more source

Tn-Seq Analysis Identifies Genes Important for Yersinia pestis Adherence during Primary Pneumonic Plague

mSphere, 2020
Following inhalation, Yersinia pestis rapidly colonizes the lung to establish infection during primary pneumonic plague. Although several adhesins have been identified in Yersinia spp., the factors mediating early Y.
Kara R. Eichelberger, Victoria E. Sepúlveda, John Ford, Sara R. Selitsky, Piotr A. Mieczkowski, Joel S. Parker, William E. Goldman   +6 more
doaj   +3 more sources

Rapid identification and typing of Yersinia pestis and other Yersinia species by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry

BMC Microbiology, 2010
Background Accurate identification is necessary to discriminate harmless environmental Yersinia species from the food-borne pathogens Yersinia enterocolitica and Yersinia pseudotuberculosis and from the group A bioterrorism plague agent Yersinia pestis ...
Drancourt Michel, Raoult Didier, Flaudrops Christophe, Ayyadurai Saravanan   +3 more
doaj   +1 more source

Inhibition of Neutrophil Primary Granule Release during Yersinia pestis Pulmonary Infection

mBio, 2019
Inhalation of Yersinia pestis causes primary pneumonic plague, the most severe manifestation of plague that is characterized by a dramatic neutrophil influx to the lungs.
Kara R. Eichelberger, Grant S. Jones, William E. Goldman   +2 more
doaj   +1 more source

Natural Mega-Focus of Yersinia pestis Main Subspecies, Antique Biovar, Phylogenetic Line 4.ANT in Gorny Altai

Проблемы особо опасных инфекций, 2018
Objective of this study was to investigate the areal of Yersinia pestis strains of antique biovar, main subspecies, phylogenetic line 4.ANT, as well as to establish the borders and spatial structure of mega-focus in the territory of Gorny Altai ...
G. A. Eroshenko, N. V. Popov, Ya. M. Krasnov, K. A. Nikiforov, A. A. Kuznetsov, A. N. Matrosov, V. V. Kutyrev   +6 more
doaj   +1 more source

Novel genetic tools for diaminopimelic acid selection in virulence studies of Yersinia pestis. [PDF]

PLoS ONE, 2011
Molecular studies of bacterial virulence are enhanced by expression of recombinant DNA during infection to allow complementation of mutants and expression of reporter proteins in vivo.
David M Bland, Nicholas A Eisele, Lauren L Keleher, Paul E Anderson, Deborah M Anderson   +4 more
doaj   +1 more source

Contribuição para o diagnóstico de peste Contribution towards plague diagnosis

Revista da Sociedade Brasileira de Medicina Tropical, 2007
Apesar de sua fundamentação clínico-epidemiológica, numerosos casos suspeitos de peste nos focos brasileiros têm sido descartados por serem negativos pelo teste de hemaglutinação para detecção de anticorpos contra o antígeno F1 da Yersinia pestis.
Alzira Maria Paiva de Almeida, Gerlane Tavares de Souza, Silvana Santos, Soraya Cavalcante Silva, Marina de Moraes Vasconcelos Petribú, Patrícia de Oliveira Haver, Antônia Ivoneida Aragão, Celso Tavares   +7 more
doaj   +1 more source

Neutrophils are resistant to Yersinia YopJ/P-induced apoptosis and are protected from ROS-mediated cell death by the type III secretion system.

PLoS ONE, 2010
BackgroundThe human innate immune system relies on the coordinated activity of macrophages and polymorphonuclear leukocytes (neutrophils or PMNs) for defense against bacterial pathogens. Yersinia spp.
Justin L Spinner, Keun Seok Seo, Jason L O'Loughlin, Jennifer A Cundiff, Scott A Minnich, Gregory A Bohach, Scott D Kobayashi   +6 more
doaj   +1 more source

Molecular Characterization of Cysteine Protease YopT from by Homology Modeling and Binding Site Identification

Drug Target Insights, 2014
Plague is a major health concern and Yersinia pestis plays the central causal role in this disease. Yersinia pestis has developed resistance against the commonly available drugs. So, it is now a key concern to find a new drug target.
Md. Anayet Hasan, S. M. Alauddin, Mohammad Ai Amin, Suza Mohammad Nur, Adnan Mannan   +4 more
doaj   +1 more source

Role of immune response in Yersinia pestis infection

Journal of Infection in Developing Countries, 2011
Yersinia pestis (Y. Pestis) is an infamous pathogen causing plague pandemics throughout history and is a selected agent of bioterrorism threatening public health. Y.
Amedeo Amedei, Elena Niccolai, Luigi Marino, Mario Milco D'Elios   +3 more
doaj   +1 more source