Results 41 to 50 of about 20,709 (178)

Iron availability and oxygen tension regulate the Yersinia Ysc type III secretion system to enable disseminated infection.

open access: yesPLoS Pathogens, 2019
The enteropathogen Yersinia pseudotuberculosis and the related plague agent Y. pestis require the Ysc type III secretion system (T3SS) to subvert phagocyte defense mechanisms and cause disease.
Diana Hooker-Romero   +9 more
doaj   +1 more source

De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence

open access: yesMicrobiologyOpen, Volume 15, Issue 4, August 2026.
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi   +2 more
wiley   +1 more source

Yersinia pestis Targets the Host Endosome Recycling Pathway during the Biogenesis of the Yersinia-Containing Vacuole To Avoid Killing by Macrophages

open access: yesmBio, 2018
Yersinia pestis has evolved many strategies to evade the innate immune system. One of these strategies is the ability to survive within macrophages. Upon phagocytosis, Y.
Michael G. Connor   +5 more
doaj   +1 more source

Vectors and Vector‐Borne Diseases: Biology, Epidemiology and Integrated Control Strategies

open access: yesJournal of Applied Entomology, Volume 150, Issue 7, Page 990-1015, August 2026.
ABSTRACT Vector‐Borne Diseases (VBDs), transmitted by arthropods such as mosquitoes, ticks, fleas and sandflies, represent a significant threat to global health. These diseases can be caused by a variety of pathogens, including bacteria, viruses, protozoa, and helminths.
Roberta Rinaldi   +4 more
wiley   +1 more source

Regulation of the Yersinia pseudotuberculosis Type III Secretion System by the CpxAR Two‐Component System

open access: yesMolecular Microbiology, Volume 126, Issue 1, Page 81-97, July 2026.
Host tissue cues including temperature, oxygen, and iron availability regulate expression of the Yersinia type III secretion system (T3SS) master regulator LcrF. We found that CpxR inhibits LcrF through an indirect, multi‐factorial mechanism and identified the osmolarity‐sensing OmpR/EnvZ system as an additional regulator of LcrF, highlighting ...
Karen Hug   +8 more
wiley   +1 more source

Parenteral iron—Does it increase infection risk?

open access: yesVox Sanguinis, Volume 121, Issue 7, Page 914-922, July 2026.
Abstract Background and Objectives Iron deficiency (ID) and iron deficiency anaemia (IDA) are prevalent conditions impacting various patient populations, both surgical and non‐surgical conditions. The advent of patient blood management (PBM) has promoted intravenous (IV) iron therapy as an alternative to oral iron and blood transfusions.
Joyisa Deb   +7 more
wiley   +1 more source

Bacteriophages fEV-1 and fD1 Infect Yersinia pestis

open access: yesViruses, 2021
Bacteriophages vB_YpeM_fEV-1 (fEV-1) and vB_YpeM_fD1 (fD1) were isolated from incoming sewage water samples in Turku, Finland, using Yersinia pestis strains EV76 and KIM D27 as enrichment hosts, respectively.
Mikael Skurnik   +6 more
doaj   +1 more source

An Uncommon Case of Ecthyma Gangrenosum in a Three‐Year‐Old Immunocompetent Child

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
The necrotic lesions on day 10. ABSTRACT Ecthyma gangrenosum (EG) is a rare cutaneous finding of Pseudomonas aeruginosa sepsis, typically in immunocompromised patients. We present EG with septic shock in a previously healthy three‐year‐old child who presented with rapidly progressing necrotic eschars and severe neutropenia.
Shobha Maharjan   +2 more
wiley   +1 more source

Omics strategies for revealing Yersinia pestis virulence

open access: yesFrontiers in Cellular and Infection Microbiology, 2012
Omics has remarkably changed the way we investigate and understand life. Omics differs from traditional hypothesis-driven research because it is a discovery-driven approach.
Ruifu eYang   +6 more
doaj   +1 more source

Bacteriophages in the Rhizosphere: Roles in Nutrient Cycling, Bacterial Community Structure, and Animal‐Mediated Dispersal

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
This review discusses bacteriophages' roles in soil ecosystems, highlighting their impact on nutrient cycling, plant health, and soil remediation, as well as animal‐mediated phage dispersal mechanisms. Overall, while bacteriophages have potential biotechnological applications, their negative effects on microbial functions and nutrient cycling highlight
Majid Komijani   +4 more
wiley   +1 more source

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