Results 61 to 70 of about 20,709 (178)

Emerging role of metagenomic next‐generation sequencing in infectious disease diagnostics: Clinical integration and future directions

mLife, Volume 5, Issue 2, Page 148-163, April 2026.
Abstract Infectious disease diagnostics has been transformed by metagenomic next‐generation sequencing (mNGS), an unbiased approach that detects bacteria, viruses, fungi, and parasites in a single assay. By sequencing all nucleic acids in a sample, mNGS overcomes the narrow detection scope and slow turnaround of conventional tests, substantially ...
Tingting Fang, Feifei Yuan, Yu Chen, Na Li, Yao Zhang, Haixia Liu, Xingchen Liu, Qing Miao, Bijie Hu   +8 more
wiley   +1 more source

From Lake Victoria to the Tap: Antibiotic Resistance and Pathogenic Contamination of Kisumu City Water Supply and Wastewater Network

Tropical Medicine &International Health, Volume 31, Issue 4, Page 547-559, April 2026.
ABSTRACT Waterborne diseases and antimicrobial resistance (AMR) pose mounting public health threats across sub‐Saharan Africa, particularly in rapidly urbanising regions dependent on untreated or poorly treated surface waters. This study applied shotgun metagenomic sequencing to characterise microbial communities, virulence factors and antibiotic ...
Oleg N. Reva, Anthony Sifuna, Francis Orata, Caroline Omolo, Jacob Stanley Iramiot, Mark C. Enright, Awelani Mutshembele, Jian Zhou, William A. Shivoga   +8 more
wiley   +1 more source

Specific Detection of Yersinia pestis Based on Receptor Binding Proteins of Phages

Pathogens, 2020
The highly pathogenic bacterium Yersinia pestis is the causative agent of plague, a notorious infectious zoonotic disease. When transmitted from person to person as pneumonic plague via droplets, Y.
Friederike Born, Peter Braun, Holger C. Scholz, Gregor Grass   +3 more
doaj   +1 more source

Catalytic Amyloids: Turning Fibrils Into Biocatalysts

Chemistry – A European Journal, Volume 32, Issue 10, 9 March 2026.
Amyloids, traditionally associated with diseases, have emerged as versatile catalytic scaffolds. From natural amyloid sequences to bioinspired and de novo designs, we highlight strategies to construct catalytic active sites and anchor enzymes onto fibrils, creating versatile nanomaterials with tunable activities. ABSTRACT Amyloids have been regarded as
Alessandra Esposito, Linda Leone, Flavia Nastri, Angela Lombardi   +3 more
wiley   +1 more source

Intercellular Communication Quorum Sensing in Pathogenic Bacteria of the Genus Yersinia

Проблемы особо опасных инфекций, 2009
The present review considered key elements of quorum sensing system of gram-negative bacteria and summarized the existing literature data on functioning features of intercellular communication system in three pathogenic Yersinia -Yersinia enterocolitica,
L. M. Koukleva, G. A. Eroshenko
doaj   +1 more source

Structural Basis of the Membrane Association by the Conserved RocS Membrane‐Targeting Sequence in Streptococcus

Advanced Science, Volume 13, Issue 17, 23 March 2026.
Chromosome segregation in Streptococcus pneumoniae depends on RocS, a bitopic protein whose membrane‐anchoring mechanisms were unclear. Using NMR and AFM, this study reveals that the widely conserved RocS anchor binds to membranes via a conserved kink‐helix motif which inserts into lipid nanodomains.
Ana Álvarez‐Mena, Estelle Morvan, Clara Lambert, Anagha Kallisseri Parambil, Martin Lefeuvre, Zeren Xu, Nadia El Mammeri, Florian Malard, Erick J. Dufourc, Cécile Feuillie, Christophe Grangeasse, Birgit Habenstein   +11 more
wiley   +1 more source

Development of a Reagent for Evaluation of Incipient Immune Response to the Live Plague Vaccine

Проблемы особо опасных инфекций, 2016
Objective of the study is to develop a reagent for the detection of lymphocytes with Yersinia pestis F1 antigen receptors. Materials and methods. Utilized have been: live plague vaccine based on the strain of Yersinia pestis EV NIIEG, formalin killed ...
P. N. Deryabin, B. V. Karal’Nik, T. G. Denisova, T. S. Ponomareva, B. B. Atshabar, G. B. Zhunusova, T. I. Tugambaev, A. A. Turuzhanova, S. B. Zakaryan, Z. T. Alymkulova   +9 more
doaj   +1 more source

Pathogenicity and virulence of Yersinia

Virulence
The genus Yersinia includes human, animal, insect, and plant pathogens as well as many symbionts and harmless bacteria. Within this genus are Yersinia enterocolitica and the Yersinia pseudotuberculosis complex, with four human pathogenic species that are
Jarett A. Seabaugh, Deborah M. Anderson
doaj   +1 more source

Isolamento da Yersinia pestis nos focos pestosos do Nordeste do Brasil no período de 1966 a 1982

Revista do Instituto de Medicina Tropical de São Paulo, 1985
No período de 1966 a 1982 foram isoladas 861 cepas de Yersinia pestis sendo 471 originadas de material de roedores e outros pequenos mamíferos, 236 de lotes de pulgas, 2 de lotes de Ornithodorus e 152 de seres humanos dos focos pestosos do Nordeste do ...
Alzira Maria Paiva de Almeida, Darci Pascoal Brasil, Francisco Gomes de Carvalho, Célio Rodrigues de Almeida   +3 more
doaj   +1 more source

EFFECT OF EXTRACHROMOSOMAL ELEMENTS OF HEREDITY ON TOXIC PROPERTIES OF YERSINIA PESTIS

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Elucidation of the role of extrachromosomal elements of heredity in manifestations of toxic properties of Yersinia pestis. Materials and methods. The study was carried out in vaccine strain Y. pestis EV76 (pMTl, pCDl, pPCPl) and non-plasmid variants
G. V. Demidova, E. P. Sokolova, V. P. Zyuzina, V. A. Rykova, I. V. Morozova, O. N. Podladchikova, V. I. Tynyanova   +6 more
doaj   +1 more source