Results 31 to 40 of about 20,709 (178)
Using Synthetic Glycans to Investigate Anti‐Glycan Antibodies and Explore Their Medical Potential
Anti‐glycan antibodies are essential in health and disease. Access to novel glycan structures paves the way for progress in antibody profiling for biomarker discovery, antibody development, and vaccine design. We summarize the strategies to synthesize and utilize synthetic glycans for the development and application of anti‐glycan antibodies in basic ...
Fabienne Weber +4 more
wiley +1 more source
Nonstationarity in wildlife disease dynamics: insights from the prairie dog–plague system
Ecological relationships often vary in strength and direction across ecosystems, a pattern that has become increasingly evident as ecology expands to broader spatial and temporal scales. Although such nonstationarity – the changing effect of predictor variables across spatiotemporal contexts – is widely acknowledged in ecological research, it has ...
Gabriel M. Barrile +6 more
wiley +1 more source
Transport of Ca2+ by Yersinia pestis [PDF]
Low-calcium-response, or Lcr, plasmids of yersiniae are known to promote an in vitro nutritional requirement for 2.5 mM Ca2+ at 37 degrees C which, if not fulfilled, results in cessation of growth with induction of virulence functions (Lcr+). The mechanism whereby Ca2+ regulates this metabolic shift is unknown.
R D, Perry, R R, Brubaker
openaire +2 more sources
Studied is the nutrient demand for growth factors among 185 Yersinia pestis strains of the main and non-main subspecies ( altaica, caucasica, hissarica , and ulegeica ) isolated in 38 natural plague foci of Russia and neighboring ...
L. M. Kukleva +4 more
doaj +1 more source
Detection of a Yersinia pestis gene homologue in rodent samples [PDF]
A homologue to a widely used genetic marker, pla, for Yersinia pestis has been identified in tissue samples of two species of rat (Rattus rattus and Rattus norvegicus) and of mice (Mus musculus and Apodemus sylvaticus) using a microarray based platform ...
Timothy A. Giles +7 more
doaj +2 more sources
Putting Rodents at the Center of One Health Programs: A Narrative Synthesis
Rodents link human, animal, and environmental health across diverse ecosystems. Rodent diversity underpins both zoonotic disease risk and ecosystem function. Environmental change reshapes rodent communities and spillover dynamics. Rodents act as reservoirs, amplifiers, and sentinels of emerging pathogens.
Steven R. Belmain
wiley +1 more source
Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo +6 more
wiley +1 more source
Oligomeric coiled-coil adhesin YadA is a double-edged sword.
Yersinia adhesin A (YadA) is an essential virulence factor for the food-borne pathogens Yersinia enterocolitica and Yersinia pseudotuberculosis. Surprisingly, it is a pseudogene in Yersinia pestis.
Salome Casutt-Meyer +5 more
doaj +1 more source
Expression and Association of the Yersinia pestis Translocon Proteins, YopB and YopD, Are Facilitated by Nanolipoprotein Particles. [PDF]
Yersinia pestis enters host cells and evades host defenses, in part, through interactions between Yersinia pestis proteins and host membranes. One such interaction is through the type III secretion system, which uses a highly conserved and ordered ...
Matthew A Coleman +12 more
doaj +1 more source
ABSTRACT Background Despite extensive documentation of the immunomodulatory effects of anthocyanidins, population‐based epidemiological studies have yet to elucidate their association with thyroid autoimmunity (TAI). Methods Using flavonoid intake data from the Flavonoid and Anthocyanidin Database (FNDDS) and 2007–2010 National Health and Nutrition ...
Mingkuan Chen +6 more
wiley +1 more source

