Results 241 to 250 of about 67,575 (268)
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Characterization of the lipopolysaccharide of Yersinia pestis

Microbial Pathogenesis, 2001
Lipopolysaccharide (LPS) extracted from eight strains of Yersinia pestis, which had been cultured at 28 or 37 degrees C, reacted equally well, in Western blots, with four monoclonal antibodies generated against the LPS from a single strain of Y. pestis cultured at 28 degrees C. LPS was extracted and purified from Y.
Richard W. Titball   +7 more
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Yersinia pestis (plague) vaccines

Expert Opinion on Biological Therapy, 2004
Live attenuated and killed whole cell vaccines against disease caused by Yersinia pestis have been available since the early part of the last century. Although these vaccines indicate the feasibility of protecting against disease, they have a number of shortcomings. The live attenuated vaccine is highly reactogenic and is not licensed for use in humans.
E. Diane Williamson, Richard W. Titball
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Pathology and Pathogenesis of Yersinia pestis

2016
Various types of animal models of plague have been developed, including mice, rats, guinea pigs, and nonhuman primates. Studies have indicated that rodent and nonhuman primate models of pneumonic plague closely resemble the human disease and that the pathologic changes that occur during bubonic plague are very similar in rodents, nonhuman primates, and
Zongmin Du, Xiaoyi Wang
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Duplex Lateral Flow Assay for the Simultaneous Detection of Yersinia pestis and Francisella tularensis.

Analytical Chemistry, 2018
High-risk pathogens such as Francisella tularensis and Yersinia pestis are categorized as highly hazardous organisms that can be used as biological weapons.
Miriam Jauset-Rubio   +5 more
semanticscholar   +1 more source

Yersinia pestis

2002
Publisher Summary Bubonic plague caused by Yersinia pestis ranks as the most severe bacterial disease known to humanity. In the mouse, this bleak process consists of an initial invasive stage characterized by the colonization of the host viscera from the dermal sites of infection caused by fleabite.
openaire   +3 more sources

Physiology of Yersinia pestis

2016
This chapter outlines the physiology of Yersinia pestis with emphasis on identifying unique functions required for tissue invasion and acute disease. These activities are opposed to often incompatible processes expressed by very closely related Yersinia pseudotuberculosis, which causes localized gastrointestinal infection. Gain of new information in Y.
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Immunobiological properties of Yersinia pestis antigens [PDF]

open access: possibleRussian Journal of Bioorganic Chemistry, 2011
The present review contains information concerning immunobiological properties of plague microbe antigens. All of the identified antigens are evaluated in relation to pathogenicity of Yersinia pestis namely a resistance to phagocytosis, toxicity, adhesiveness etc. as well as persistence ability and adaptation to variable environment.
A. A. Byvalov, Yu. S. Ovodov
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Plague: Yersinia pestis

2010
Bubonic plague is a flea-borne zoonosis caused by the Gram-negative bacterium Yersinia pestis, which mainly affects small burrowing mammals including domestic rats. Human disease occurs in endemic countries—currently mainly in Africa (including Madagascar)—following bites from fleas recently hosted by a bacteraemic animal.
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Yersinia enterocolitica and Yersinia pestis

2018
The genus Yersinia consists of 17 species, of which Y. enterocolitica, Y. pseudotuberculosis, and Y. pestis are pathogenic to humans. The former two are enteropathogenic and responsible for gastroenteritis, and the latter one is responsible for the plague. Y. enterocolitica and Y.
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Genetic Regulation of Yersinia pestis

2016
Y. pestis exhibits dramatically different traits of pathogenicity and transmission, albeit their close genetic relationship with its ancestor-Y. pseudotuberculosis, a self-limiting gastroenteric pathogen. Y. pestis is evolved into a deadly pathogen and transmitted to mammals and/or human beings by infected flea biting or directly contacting with the ...
Haihong Fang   +3 more
openaire   +2 more sources

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