Results 51 to 60 of about 778 (189)

Evidence for numerous analogs of yessotoxin in Protoceratium reticulatum

open access: yes, 2005
A solid-phase extract from Protoceratium reticulatum was partitioned between water and butanol and the two fractions purified on an alumina column. Fractionation was monitored by ELISA and LC\u2013MS. Results indicate that while almost all yessotoxin (1)
Quilliam, Michael A.   +10 more
core   +1 more source

Different toxic effects of YTX in tumor K-562 and lymphoblastoid cell lines

open access: yesFrontiers in Pharmacology, 2015
Yessotoxin (YTX) modulates cellular phosphodiesterases (PDEs). In this regard, opposite effects had been described in the tumor model K-562 cell line and fresh human lymphocytes in terms of cell viability, cyclic adenosine 3´,5´-cyclic monophosphate ...
Andrea Fernández Araújo   +4 more
doaj   +1 more source

Morphological, Phylogenetic and Toxinological Characterization of Potentially Harmful Algal Species from the Marine Coastal Waters of Buenos Aires Province (Argentina)

open access: yesPhycology, 2023
In the framework of a monitoring program of harmful microalgae from the marine coastal waters of the Buenos Aires Province, seven strains were isolated and characterized by morphological and molecular analysis (LSU rDNA partial sequencing, D1–D3 regions).
Jonás Adrián Tardivo Kubis   +5 more
doaj   +1 more source

Current situation on analysis of marine toxins

open access: yesReviews in Analytical Chemistry, 2013
Marine toxins are a food safety concern worldwide. This review discusses current analytical methods for those toxins that are legally regulated in Europe, namely domoic acid, saxitoxin, okadaic acid, yessotoxin, pectenotoxin and azaspiracids, and all ...
Botana Ana M.   +4 more
doaj   +1 more source

Use of Biosensors as Alternatives to Current Regulatory Methods for Marine Biotoxins

open access: yesSensors, 2009
Marine toxins are currently monitored by means of a bioassay that requires the use of many mice, which poses a technical and ethical problem in many countries.
Luis M. Botana   +3 more
doaj   +1 more source

Convenient Large-Scale Purification of Yessotoxin from Protoceratium reticulatum Culture and Isolation of a Novel Furanoyessotoxin

open access: yes, 2016
Yessotoxins from a large-scale culture (226 L) of Protoceratium reticulatum strain CAWD129 were harvested by filtration followed by solid-phase extraction.
Jared I. Loader (2435521)   +8 more
core   +1 more source

Synthesis of the ABCDEF and FGHI ring system of yessotoxin and adriatoxin [PDF]

open access: yesThe Journal of Antibiotics, 2016
Yessotoxin and adriatoxin are members of the polycyclic ether family of marine natural products. Outlined in this article is our synthetic approach to two subunits of these targets. Central to our strategy is a coupling sequence that employs an olefinic-ester cyclization reaction. As outlined, this sequence was used in two coupling sequences. First, it
Zhang, Yuan, Rainier, Jon D.
openaire   +3 more sources

Lipophilic Toxin Profile in Mytilus galloprovincialis during Episodes of Diarrhetic Shellfish Poisoning (DSP) in the N.E. Adriatic Sea in 2006

open access: yesMolecules, 2011
Dinophysis spp. blooms and related shellfish toxicity events of diarrhetic shellfish poisoning (DSP) have been the most reported toxicity event through the Croatian National monitoring program.
Sanda Skejic   +7 more
doaj   +1 more source

Toxicity and Growth Assessments of Three Thermophilic Benthic Dinoflagellates (Ostreopsis cf. ovata, Prorocentrum lima and Coolia monotis) Developing in the Southern Mediterranean Basin

open access: yesToxins, 2016
Harmful benthic dinoflagellates, usually developing in tropical areas, are expanding to temperate ecosystems facing water warming. Reports on harmful benthic species are particularly scarce in the Southern Mediterranean Sea.
Hela Ben-Gharbia   +9 more
doaj   +1 more source

Vacuolization as a Novel Approach to Cancer Therapy

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 6, June 2026.
This review discusses the novel strategy of inducing vacuole formation in cancer cells using small molecules, that induce nonapoptotic cell death mechanisms, such as paraptosis, oncosis, autophagy, and methuosis, and its potential in overcoming resistance to apoptosis‐based cancer therapies.
Mariah Pasternak   +9 more
wiley   +1 more source

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