Results 131 to 140 of about 639,780 (268)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Combining ability analysis for yield and yield components in bold grained rice (Oryza sativa L.) of Assam

Acta Agronómica, 2009
Combining ability analysis for grain yield and its components was carried out in eight parental diallel crosses of bold grained rice excluding reciprocals.
B.K. Dutta, S.B. Paul, R Chakraborty, Supriyo Chakraborty   +3 more
doaj  

A genome-wide association study identified loci for yield component traits in sugarcane (Saccharum spp.). [PDF]

PLoS One, 2019
Barreto FZ, Rosa JRBF, Balsalobre TWA, Pastina MM, Silva RR, Hoffmann HP, de Souza AP, Garcia AAF, Carneiro MS.   +8 more
europepmc   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Spatial transcriptomics identifies distinct domains regulating yield-component traits of the wheat ear. [PDF]

Sci Adv
Qu Y, Tan C, Yang L, Pasquariello M, Alabdullah AK, Sun S, Iqbal M, Salamon J, Boden SA.   +8 more
europepmc   +1 more source

An APETALA1 ortholog affects plant architecture and seed yield component in oilseed rape (Brassica napus L.). [PDF]

BMC Plant Biol, 2018
Shah S, Karunarathna NL, Jung C, Emrani N.   +3 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Correction: Yield and yield component trait analysis with DArT genotyping for GWAS in soybean grown in drought conditions of Kazakhstan. [PDF]

Front Plant Sci
Amangeldiyeva A, Yerzhebayeva R, Mazkirat S, Didorenko S, Bastaubayeva S, Maikotov B, Kassenov R, Jenisbayeva A, Shavrukov Y.   +8 more
europepmc   +1 more source

Identification of marker-trait associations for morphological descriptors and yield component traits in sugarcane. [PDF]

Physiol Mol Biol Plants, 2017
Siraree A, Banerjee N, Kumar S, Khan MS, Singh PK, Kumar S, Sharma S, Singh RK, Singh J.   +8 more
europepmc   +1 more source