Results 251 to 260 of about 6,822,950 (366)

Combining biocatalytic and radical retrosynthesis for efficient chemoenzymatic synthesis of natural products.

Chem Soc Rev
Renata H.
europepmc   +1 more source

Effect of Forced Shear Sliming and Slime Removal on the Flotation and Particle-Bubble Mineralization of Lignite. [PDF]

ACS Omega
Xia Y, Li Y, Zhang D, Guo D.
europepmc   +1 more source

Single‐cell transcriptomics redefines focal neuroendocrine differentiation as a distinct prostate cancer pathology

Molecular Oncology, EarlyView.
Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban, Shivakumar Keerthikumar, Ashlee Clark, Hong Wang, Belinda Phipson, Andrew Bakshi, Andrew Ryan, Heather Thorne, Renea A. Taylor, Mitchell G. Lawrence, Gail P. Risbridger, Roxanne Toivanen, David L. Goode   +12 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

Molecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik, Shi Pan, Eloise Withnell, Hou Wang Lam, Maria Secrier   +4 more
wiley   +1 more source

Effects of crushed wheat straw with plastic film mulch on soil hydrothermal properties and water use efficiency of sunflower in the northwestern arid region of China. [PDF]

Sci Rep
Zhang J, Ren F, Zhang R, Ding L, Li F, Li X, Zhong T, Yin M, Du L, Yang R, Tian P.   +10 more
europepmc   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

Molecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun, Ching‐Fang Yu, Sheng‐Yan Wu, Wei‐Chung Cheng, Chi‐Shiun Chiang, Fang‐Hsin Chen   +5 more
wiley   +1 more source

Leveraging a novel nanocomposite for enhanced drilling fluid efficiency. [PDF]

Sci Rep
Tian Y, Altalbawy FMA, Rachchh N, Ramachandran T, Shankhyan A, Karthikeyan A, Thatoi DN, Gupta D, Norberdiyeva M, Al-Badkubi MRKM, Mottaghi M.   +10 more
europepmc   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Metabolic engineering of Saccharomyces cerevisiae for neoxanthin production. [PDF]

Microb Cell Fact
Arenas N, Cataldo VF, Agosin E.
europepmc   +1 more source

Principles of nutrition-dependent root-microbiome engineering for regulating crop yield via live microbial inoculants

Yuxiao Huang, Shuzhu Tang, Rumeng Liu, Liu Ju, Ting Xiao, Bing Ni   +5 more
openalex   +1 more source