Results 251 to 260 of about 494,286 (303)

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Flexural Behavior of Reinforced Concrete Two-Way Slabs Strengthened with Basalt Fiber-Reinforced Polymer Grid and Engineered Cementitious Composite. [PDF]

Materials (Basel)
Xue J, Zhu M, Liang H, Li H.
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Advances in CRISPR Plant Applications. [PDF]

Int J Mol Sci
Jing L, Roy D, Kalischuk M.
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Enhanced Biomass and Protein Synthesis in Engineered <i>Cyberlindnera jadinii</i> Growing on Ethanol/Acetate: Metabolic Engineering and Transcriptomic Mechanism. [PDF]

Foods
Cao Y, Ma L, Li Y, Zhu Z, Duan Y, Bai W, Long L, Shi P, Chen L, Li D.   +9 more
europepmc   +1 more source

Enhanced visible-light photoredox catalysis with rubicene-embedded polycyclic aromatic hydrocarbons (PAHs). [PDF]

Chem Sci
Mi C, Ma L, Wen X, Hou Y, Dao X, Peng A, Shi Q, Huang H.   +7 more
europepmc   +1 more source

Recent Advances in Beta-Alanine Production via Enzymatic Catalysis and Microbial Whole-Cell Catalysis. [PDF]

Biology (Basel)
Yu J, Ma P, Zhang J, Zhang H, Tie H, Ruan H.   +5 more
europepmc   +1 more source

Automatic determination of mechanical properties from Molecular Dynamic Stress-Strain curves using Regression Fringe Response. [PDF]

Commun Eng
Kemppainen J, Muzzy T, Wavrunek TK, Odegard GM.   +3 more
europepmc   +1 more source