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A Technique to Achieve Maximal Manufacturing Yield in Engineering Design
Engineering Optimization, 2002Techniques to maximize manufacturing yield of an engineering design for mass manufactured products are well established. These techniques may be broadly grouped into geometrical and statistical techniques. The geometrical techniques suffer from the curse of dimensionality and therefore become very expensive when applied to problems with a large number ...
Jayaram, J.S.R. +3 more
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Metabolic engineering of tomato for high-yield production of astaxanthin
Metabolic Engineering, 2013Dietary carotenoids have been shown to be beneficial to health by decreasing the risk of many diseases. Attempts to enhance carotenoids in food crops have been successful although higher plants appear to resist big changes of carotenoid biosynthesis by metabolic engineering.
Jun-Chao, Huang +4 more
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Technical note: The yield stress—An engineering reality
Journal of Rheology, 1989A simple experiment using the falling ball technique was used to demonstrate unambiguously that a 2500 wppm aqueous Carbopol 960 solution has a yield stress. A series of photographs taken over a period of several months revealed that a nylon ball with a density of 1.156 g/cm3 showed no measurable movement when placed well within a Carbopol solution ...
James P. Hartnett, Robert Y. Z. Hu
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Metabolic engineering for the high-yield production of polydatin in Yarrowia lipolytica
Bioresource Technology, 2023Polydatin, a glycosylated derivative of resveratrol, has better structural stability and biological activity than resveratrol. Polydatin is the extract of Polygonum cuspidatum, which has various pharmacological effects. Owing to its Crabtree-negative characteristics and high supply of malonyl-CoA, Yarrowia lipolytica was selected to produce polydatin ...
Yanzhe Shang +4 more
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Engineering Methyltransferase and Sulfoxide Synthase for High-Yield Production of Ergothioneine
Journal of Agricultural and Food Chemistry, 2022Ergothioneine (ERG) is an unusual sulfur-containing amino acid with antioxidant activity that can be synthesized by certain bacteria and fungi. Microbial fermentation is a promising method for ERG production. In this study, the bifunctional enzyme methyltransferase-sulfoxide synthase NcEgt1 from Neurospora crassa was truncated to obtain sulfoxide ...
Luwen Zhang +3 more
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Metabolic engineering of Escherichia coli for high-yield uridine production
Metabolic Engineering, 2018Uridine is a kind of pyrimidine nucleoside that has been widely applied in the pharmaceutical industry. Although microbial fermentation is a promising method for industrial production of uridine, an efficient microbial cell factory is still lacking. In this study, we constructed a metabolically engineered Escherichia coli capable of high-yield uridine ...
Heyun Wu +10 more
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Genetic engineering of peppermint for improved essential oil composition and yield
Transgenic Research, 2005The biochemistry, organization, and regulation of essential oil metabolism in the epidermal oil glands of peppermint have been defined, and most of the genes encoding enzymes of the eight-step pathway to the principal monoterpene component (-)-menthol have been isolated. Using these tools for pathway engineering, two genes and two expression strategies
Mark R, Wildung, Rodney B, Croteau
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High‐yield anthocyanin biosynthesis in engineered Escherichia coli
Biotechnology and Bioengineering, 2007AbstractAnthocyanins are red, purple, or blue plant water‐soluble pigments. In the past two decades, anthocyanins have received extensive studies for their anti‐oxidative, anti‐inflammatory, anti‐cancer, anti‐obesity, anti‐diabetic, and cardioprotective properties. In the present study, anthocyanin biosynthetic enzymes from different plant species were
Yajun, Yan +2 more
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Metabolic engineering of Gluconobacter oxydans 621H for increased biomass yield
Applied Microbiology and Biotechnology, 2017The obligatory aerobic acetic acid bacterium Gluconobacter oxydans incompletely oxidizes carbon sources regio- and stereoselectively in the periplasm and therefore is used industrially for oxidative biotransformations, e. g., in vitamin C production.
Ines Kiefler +2 more
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Metabolic engineering to increase crop yield: From concept to execution
Plant Science, 2018Although the return on investment over the last 20 years for mass screening of individual plant genes to improve crop performance has been low, the investment in these activities was essential to establish the infrastructure and tools of modern plant genomics.
Frank A, Skraly +3 more
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