Results 71 to 80 of about 1,733,424 (331)

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Dentz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Biotechnology and bioeconomy of complex traits in crop plants

BioTechnologia, 2017
Most important crop productivity traits, such as yield under normal and environmental stress conditions, are determined by a large number of genes, each with a small phenotypic effect.
Jan Antoni Rafalski
doaj   +1 more source

Metabolic engineering of a thermophilic bacterium to produce ethanol at high yield [PDF]

Proceedings of the National Academy of Sciences, 2008
We report engineering Thermoanaerobacterium saccharolyticum , a thermophilic anaerobic bacterium that ferments xylan and biomass-derived sugars, to produce ethanol at high yield. Knockout of genes involved in organic acid formation (acetate kinase, phosphate acetyltransferase, and L-lactate dehydrogenase) resulted ...
A Joe, Shaw, Kara K, Podkaminer, Sunil G, Desai, John S, Bardsley, Stephen R, Rogers, Philip G, Thorne, David A, Hogsett, Lee R, Lynd   +7 more
openaire   +2 more sources

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

Experimental Evaluation of Hysteretic Behavior of Rhombic Steel Plate Dampers

Advances in Mechanical Engineering, 2014
Rhombic mild-steel plate damper (also named rhombic added damping and Stiffness (RADAS)) is a newly proposed and developed bending energy dissipation damper in recent years, and its mechanical properties, seismic behavior, and engineering application ...
Qiang Han, Junfeng Jia, Zigang Xu, Yulei Bai, Nianhua Song   +4 more
doaj   +1 more source

Astaxanthin overproduction in yeast by strain engineering and new gene target uncovering

Biotechnology for Biofuels, 2018
Background Astaxanthin is a natural carotenoid pigment with tremendous antioxidant activity and great commercial value. Microbial production of astaxanthin via metabolic engineering has become a promising alternative.
Jin Jin, Ying Wang, Mingdong Yao, Xiaoli Gu, Bo Li, Hong Liu, Mingzhu Ding, Wenhai Xiao, Yingjin Yuan   +8 more
doaj   +1 more source

Biosynthesis and metabolic engineering of 1-hydroxyphenazine in Pseudomonas chlororaphis H18

Microbial Cell Factories, 2021
Background 1-Hydroxyphenazine (1-OH-PHZ) is a phenazine microbial metabolite with broad-spectrum antibacterial activities against a lot of plant pathogens. However, its use is hampered by the low yield all along.
Yupeng Wan, Hongchen Liu, Mo Xian, Wei Huang   +3 more
doaj   +1 more source

Natural and engineered cyclodipeptides: Biosynthesis, chemical diversity, and engineering strategies for diversification and high-yield bioproduction.

Engineering Microbiology, 2023
Cyclodipeptides are diverse chemical scaffolds that show a broad range of bioactivities relevant for medicine, agriculture, chemical catalysis, and material sciences. Cyclodipeptides can be synthesized enzymatically through two unrelated enzyme families,
Wahyu Setia Widodo, Sonja Billerbeck
doaj   +1 more source

Ribosome Pool Engineering Increases Protein Biosynthesis Yields

ACS Central Science
The biosynthetic capability of the bacterial ribosome motivates efforts to understand and harness sequence-optimized versions for synthetic biology. However, functional differences between natively occurring ribosomal RNA (rRNA) operon sequences remain poorly characterized. Here, we use an in vitro ribosome synthesis and translation platform to measure
Camila Kofman, Jessica A. Willi, Ashty S. Karim, Michael C. Jewett   +3 more
openaire   +3 more sources

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source