Results 91 to 100 of about 44,314 (257)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Yield per Recruit and Spawning per Recruit of Brownbanded Bamboo Shark, Chiloscyllium punctatum in Southeast Asia

Yield per Recruit and Spawning per Recruit of Brownbanded Bamboo Shark, Chiloscyllium punctatum in Southeast Asia
The brownbanded bamboo shark (Chiloscyllium punctatum) is a benthic shark species distributed in Southeast Asia. The species has been listed as “Near Threatened” by the IUCN, but only based on indirect information. In this study, yield per recruit (YPR) and spawning per recruit (SPR) analyses were conducted to determine the current stock status.
openaire   +1 more source

Growth, Mortality, and Yield per Recruit of Synodontis schall (Bloch and Schneider, 1801) in Roseries Reservoir, Sudan

Asian Journal of Fisheries and Aquatic Research
This study assessed the population bio-parameters of shield-head catfish Synodontis schall (Bloch & Schneider, 1801) in the Roseries Reservoir (Sudan), using length-frequency data analyzed with FiSAT software. The von Bertalanffy growth parameters were determined as an asymptotic length (L∞) of 50.4 cm, and a growth curvature (K) of 0.17 yr.⁻¹ ...
Shuaib, Mujtaba El Khair, Abdalla, Mutasim Yousif Mohamed, Alttagi, Zeinab El Amin Alsharif, Hamid, Abdalla Mustafa   +3 more
openaire   +2 more sources

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Yield per recruit of the peacock bass Cichla monoculus (Spix and Agassiz, 1831) caught in Lago Grande at Manacapuru (Amazonas – Brazil)

Brazilian Journal of Biology
We evaluated the stock of peacock bass Cichla monoculus caught by a small-scale fishing fleet in Lago Grande at Manacapuru. The database was constructed by monthly samplings of 200 fish between February 2007 and January 2008. We measured the total length
CP Campos, CEC Freitas
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Sinusoidal growth, recruitment, mortality, yield-per-recruit analysis of Buried fan scallop Mimachlamys funebris (Reeve, 1853) and their implications for mariculture

Journal of Fisheries, 2020
This study described the growth, mortality, recruitment pattern and exploitation rate of the Buried fan scallop (Mimachlamys funebris) in Asid Gulf, Philippines.
Ian Cris R. Buban, Christian D. Cabiles, Renan U. Bobiles, Alex P. Camaya, Victor S. Soliman   +4 more
doaj  

Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells

FEBS Letters, EarlyView.
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park, Inho Kwon, Yong Hwan Kim, Ji‐Eun Bae, Joon Bum Kim, Seong Hyun Kim, Sungho Maeng, Doo Sin Jo, Dong‐Hyung Cho   +8 more
wiley   +1 more source