Results 51 to 60 of about 6,926,535 (359)

Strength properties of the Bambara kernel (Vigna subterranean) as influenced by the moisture content and kernel size

Research in Agricultural Engineering, 2022
The fracture resistance of food grains is an essential piece of information required for the optimum design and development of agricultural post-harvest machinery.
Nnaemeka R. Nwakuba, Osita C. Chukwuezie, Maxwell I. Chikwue, Chibuike Ononogbo, Cyprian Dirioha, Merlin Simo-Tagne   +5 more
doaj   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

An interpretable stacking ensemble model for high-entropy alloy mechanical property prediction

Frontiers in Materials
High-entropy alloys (HEAs) have attracted significant attention due to their excellent mechanical properties and broad application prospects. However, accurately predicting their mechanical behavior remains challenging because of the vast compositional ...
Songpeng Zhao, Zeyuan Li, Changshuai Yin, Zhaofu Zhang, Teng Long, Jingjing Yang, Ruyue Cao, Yuzheng Guo   +7 more
doaj   +1 more source

Deformation mechanisms in a metastable beta titanium twinning induced plasticity alloy with high yield strength and high strain hardening rate

Acta Materialia, 2018
Metastable β titanium alloys with both twinning (TWIP) and martensite transformation (TRIP) usually exhibit a low yield strength of between 200 and 500 MPa, but high strain hardening rate and large uniform elongation.
Junheng Gao, Yuhe Huang, Dikai Guan, A. J. Knowles, Le Ma, D. Dye, W. Rainforth   +6 more
semanticscholar   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Simulation and Experimental Study on the Inhomogeneity of Mechanical Properties of Aluminum Alloy 7050 Plate

Metals, 2020
In this work, the finite element method simulated the symmetrical hot rolling process of 7050 aluminum alloy plate. The simulation result show that different thickness layers of 7050 aluminum alloy plate experienced different temperature and strain ...
Hai Gong, Xuan Cao, Yaoqiong Liu, Yunxin Wu, Fangmin Jiang, Minghai Zhang   +5 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source