Results 61 to 70 of about 3,511,649 (249)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Science and Technology of Advanced MaterialsWire-feed additive manufacturing (WFAM) produces superalloys with complex thermal cycles and unique microstructures, often requiring optimized heat treatments.
Xin Wang +4 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
A STUDY ON THE YIELD STRENGTH OF BCC LATTICED METALS AND ALLOYS
, 2015 In this study, a mathematical approach was presented to theoretically determine the change of the yield strength of bcc metals and alloys with temperature and strain rate, which can be determined for any desired strain rate by conducting experiments at ...
Said, G., Aktas, D., Aytekin, H.
core +1 more source
Modelling of behaviour of metals at high strain rates [PDF]
, 2006 The aim of the work presented in this thesis was to produce the improvement of the existing simulation tools used for the analysis of materials and structures, which are dynamically loaded and subjected to the different levels of temperatures and strain ...
Panov, Vili
core +5 more sources
A clinically applicable energy-based approach for evaluating bone strength
Bone & Joint ResearchAims: Bone mineral density (BMD) is the diagnostic standard for osteoporosis but reflects only part of bone mass change. Testing bone yield strength is a better measure of biomechanical competence, yet requires destructive testing.
Qiushi Bai +11 more
doaj +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Strength modelling of Al-Cu-Mg Type alloys
, 2006 Age hardening of Al-Cu-Mg type alloys occurs in two stages separated by a constant hardness plateau when the alloys are aged at 110°C to 240?C after solution treatment and quenching.
Yan, Jialin
core +1 more source
Investigation of the Solid Solution Hardening Mechanism of Low-Alloyed Copper–Scandium Alloys
MetalsThe addition of alloying elements is a crucial factor in improving the mechanical properties of pure copper, particularly in terms of enhancing its yield strength and hardness.
Ramona Henle +6 more
doaj +1 more source
Mechanical Properties of Nanoporous Au: From Empirical Evidence to Phenomenological Modeling
Metals, 2015 The present work focuses on the development of a theoretical model aimed at relating the mechanical properties of nanoporous metals to the bending response of thick ligaments.
Giorgio Pia, Francesco Delogu
doaj +1 more source