Results 81 to 90 of about 3,511,649 (249)

Evaluating Strengthening and Impact Toughness Mechanisms for Ferritic and Bainitic Microstructures in Nb, Nb-Mo and Ti-Mo Microalloyed Steels

Metals, 2017
Low carbon microalloyed steels show interesting commercial possibilities by combining different “micro”-alloying elements when high strength and low temperature toughness properties are required. Depending on the elements chosen for the chemistry design,
Gorka Larzabal, Nerea Isasti, Jose M. Rodriguez-Ibabe, Pello Uranga   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

The Effective Utilization of Yield Strength

, 1971
In many structural and constructional applications (such as pressure vessels), steels, particularly high-yield-strength steels, are not being utilized as effectively as may be possible.
J. H. Gross
core   +1 more source

Synergistic effect of Nb and Ta alloying on microstructure and mechanical properties of CoCrFeNi high-entropy alloy

Cailiao gongcheng
CoCrFeNi-(Nb, Ta) high-entropy alloys (HEAs) were prepared by a vacuum arc melting process, and the synergistic effect of Nb and Ta concentrations on the microstructure evolution and mechanical properties was investigated in detail.
ZHU Zhe, SHI Zengmin, YE Xicong, WANG Kesheng, LEI Haofeng, DENG-LI Chengui, LI Guangyu, DAI Lei   +7 more
doaj   +1 more source

The Prediction of the Mechanical Properties for Dual-Phase High Strength Steel Grades Based on Microstructure Characteristics

Metals, 2018
The decrease of emissions from vehicle operation is connected mainly to the reduction of the car’s body weight. The high strength and good formability of the dual phase steel grades predetermine these to be used in the structural parts of the car’s body ...
Emil Evin, Ján Kepič, Katarína Buriková, Miroslav Tomáš   +3 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Mass selection in maize composites by means of selection indices [PDF]

, 1972
General considerationsA selection index may be applied to selection based either upon the performance of single plants or upon the performance of progenies.
Wolff, F., de
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Dynamically Recrystallized Microstructures, Textures, and Tensile Properties of a Hot Worked High-Mn Steel

Metals, 2019
The deformation microstructures and mechanical properties were studied in a high-Mn steel subjected to hot compression. The deformation microstructures resulted from the development of dynamic recrystallization (DRX).
Pavel Dolzhenko, Marina Tikhonova, Rustam Kaibyshev, Andrey Belyakov   +3 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source