Results 51 to 60 of about 427,988 (311)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Discussion of ‘‘Re-Examination of Undrained Strength at Atterberg Limits Water Contents’’ by H.B. Nagaraj, A. Sridharan & H.M. Mallikarjuna [PDF]

, 2012
Having recently investigated soil strength at the Atterberg limits, the discussers read the paper by Nagaraj et al. (2012) with interest. Whilst some of the conclusions of the paper concur with those of our own work, there are other areas in which we ...
Haigh, S K, Vardanega, P J
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An interpretable stacking ensemble model for high-entropy alloy mechanical property prediction

Frontiers in Materials
High-entropy alloys (HEAs) have attracted significant attention due to their excellent mechanical properties and broad application prospects. However, accurately predicting their mechanical behavior remains challenging because of the vast compositional ...
Songpeng Zhao, Zeyuan Li, Changshuai Yin, Zhaofu Zhang, Teng Long, Jingjing Yang, Ruyue Cao, Yuzheng Guo   +7 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Simulation and Experimental Study on the Inhomogeneity of Mechanical Properties of Aluminum Alloy 7050 Plate

Metals, 2020
In this work, the finite element method simulated the symmetrical hot rolling process of 7050 aluminum alloy plate. The simulation result show that different thickness layers of 7050 aluminum alloy plate experienced different temperature and strain ...
Hai Gong, Xuan Cao, Yaoqiong Liu, Yunxin Wu, Fangmin Jiang, Minghai Zhang   +5 more
doaj   +1 more source

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

Microstructural Evolution and Tensile Properties of Nb-V-Ti-N Microalloyed Steel with Varying Nitrogen Contents

Metals
With the rapid development of long-distance transmission pipelines for oil and natural gas, pipeline steel is continuously evolving towards higher pressure, larger diameter, and thicker wall thickness.
Jiangcheng Liu, Kai Guo, Haote Ma, Jiangli He, Junchao Wang, Chuanyou Zhang, Tiansheng Wang, Qingfeng Wang   +7 more
doaj   +1 more source

Effect of Relative Thickness Reduction and Heat Treatment on AMS 5596 Sheet Mechanical Properties After Flow Forming [PDF]

Archives of Metallurgy and Materials, 2019
In the paper the results of experimental research of the process of flow forming of cylindrical drawpieces were presented. The drawpieces were made of the 3.1 mm thick AMS 5596 sheet by drawing process.
S. Kut, P. Maj, T. Mrugała
doaj   +1 more source