Results 131 to 140 of about 8,550,318 (390)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
MiningThe presence of free muscovite in tailings can negatively affect the mechanical strength and rheological properties of cemented paste backfill, as has been observed for several cementitious materials. The aim of this study is to evaluate the influence of
Hadj Ghani Menasria +3 more
doaj +1 more source
Aggregate Structures and Solid-Liquid Separation Processes
KONA Powder and Particle Journal, 2014 Solid-liquid separation processes for dispersions of fine particles continue to present significant challenges in many areas. As an example, in filtration it is usually possible to achieve either fast filtration or a
Simon Biggs
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
QUANTITATIVE ASSESSMENT OF THE YIELD STRESS OF FERRITE-PEARLITIC STEELS BY STRUCTURE PARAMETERS
, 2021 A. T. Kanayev +2 more
openalex +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Development of a continuum plasticity model for the commercial finite element code ABAQUS [PDF]
, 2011 The present work relates to the development of computational material models for sheet metal forming simulations. In this specific study, an implicit scheme with consistent Jacobian is used for integration of large deformation formulation and plane ...
De Waele, Wim, Safaei, Mohsen
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The Effect of Chlormequat Chloride on Yield and Yield Components of Three Wheat Cultivars under Drought Stress Conditions [PDF]
, 2016 KH. Rokhafrooz +2 more
openalex +1 more source