Results 191 to 200 of about 1,214,521 (291)

Electrochemical desulfurative borylation of thiols, disulfides, thioethers and thioacetals. [PDF]

Nat Commun
Kuzmin J, Margarita C, Winter J, Lundberg H.   +3 more
europepmc   +1 more source

Effect of Micronutrient Application with Different Sources of NPK on Growth and Yield of Finger Millet Crop in Red Laterite Zone [PDF]

, 2019
Korla Aditya Chowdary, B. C. Patra
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Morphological analysis-based yield modeling in greenhouse grown cherry tomato (<i>Solanum lycopersicum</i>) under prolonged heat stress. [PDF]

Front Plant Sci
Kim S, Jeong J, Kim S.
europepmc   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

A Multicatalytic Cascade for the Stereoselective Synthesis of 1,4-Chiral Nitro Alcohols. [PDF]

Org Lett
Ascaso-Alegre C, Linacero-Gracia Á, Ferreira P, Herrera RP, Mangas-Sánchez J.   +4 more
europepmc   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Highly Efficient Organocatalytic House-Meinwald Rearrangement for the Facile Synthesis of Aldehydes: Swift Access to Ibuprofen. [PDF]

Chemistry
Dressler F, Fdali IE, Ciezarek LL, Schreiner PR.   +3 more
europepmc   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Engineering Carbon Nitride Quantum Dots via Sulfur Doping for Controlled Reactive Oxygen Species Generation. [PDF]

Glob Chall
Belko N, Maltanava H, Brezhneva N, Tamarov K, Lehto VP, Moilanen JO, Leskinen JTT, Semenov D, Filonenko E, Koshevoy I, Schneidewind J, De Vos WH, Kuzhir P.   +12 more
europepmc   +1 more source