Results 11 to 20 of about 30 (29)

拉米夫定抗HBV治疗过程中HBV-DNA的反弹规律及变异研究 附视频

Zhongguo shiyan zhenduanxue, 2002
目的　观察拉米夫定抗HBV治疗过程HBV DNA的反弹规律及变异情况。方法　单一采用拉米夫定 (1 0 0mg/d)治疗 83例有活动性病毒复制的慢性乙型肝炎患者 (CHB) ,应用荧光全定量PCR检测CHB治疗前和治疗 2、6、1 2、1 8个月后血清HBV DNA的含量 ,应用UniArray技术检测YMDD位点突变。结果　根据HBV DNA含量的下降、波动、反弹分 3种类型 :A类 2 8例 ,HBV DNA含量呈直线下降 ,无HBV基因突变 ;B类 2 3例 ,HBV DNA含量先下降、后反弹 ...
陈然峰, 陈国军, 董长林, 陈孟春, 金晓东, 杨勇, 1.武警浙江省总队医院检验科, 2.武警浙江省总队医院检验科, 3.武警浙江省总队医院检验科, 4.武警浙江省总队医院检验科, 5.武警浙江省总队医院检验科, 6.武警浙江省总队医院检验科 浙江嘉兴314000, 7.浙江嘉兴314000, 8.浙江嘉兴314000, 9.浙江嘉兴314000, 10.浙江嘉兴314000, 11.浙江嘉兴314000   +16 more
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阿德福韦酯致范可尼综合征1例报告

Zhongguo shiyan zhenduanxue, 2018
1病例资料患者男性,64岁,于2009年6月明确诊断为"慢性乙型肝炎",应用拉米夫定抗病毒治疗1年后出现HBVDNA反弹,YMDD变异,遂改用拉米夫定联合阿德福韦酯抗病毒治疗后HBVDNA定量逐渐下降,病情稳定。2013年3月改用恩替卡韦联合阿德福韦酯抗病毒治疗,病情稳定。2014年10月开始出现间断胸背部、腰部、双下肢疼痛 ...
郑瑞琦, 于慧慧, 郭丰昌, 胡玉琳   +3 more
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[Exploring the effects of entecavir treatment on the degree of liver fibrosis in patients with non-alcoholic fatty liver combined with chronic hepatitis B in Tibet region]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2022
Wen QP, Qian H, Ba S, Lu MJ, Silang LDJ, Shi L.   +5 more
europepmc   +1 more source

[Antiviral therapy and clinical cure for chronic hepatitis B in children: progress and challenges]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2021
Zhang M, Li J, Wang FS.
europepmc   +1 more source

反向斑点杂交技术检测HBV YMDD基序变异 的应用和评价

Zhongshan Daxue xuebao. Yixue kexue ban, 2009
【目的】 采用反向斑点杂交技术对拉米夫定治疗后的慢性乙型肝炎患者血清中HBV YMDD基序变异进行检测,并对其临床应用进行方法学评价65377;【方法】 提取242例慢性乙型肝炎患者血清中HBV DNA,经聚合酶链反应后进行膜条杂交并同测序比较分析检测结果的一致性,随后对该方法进行灵敏度和混合感染检测能力的评价65377;【结果】 242例样本检测结果有236例与测序结果相符,反向斑点杂交检测结果同测序结果的符合率达97.5%;混合型感染58例,占样品总数的24%65377;反向斑点杂交技术检测HBV ...
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[Progress in the research of HBV reactivation in patients undergoing hematopoietic stem cell transplantation]. [PDF]

Zhonghua Xue Ye Xue Za Zhi, 2021
Niu JX, Xu Y, Wu DP.
europepmc   +1 more source

[One case of newly-onset liver cancer and dual drug-resistance during treatment of hepatitis B cirrhosis with nucleos(t)ide analogues]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2016
Li CY, Pan JY, Yang AP.
europepmc   +1 more source

[A randomized controlled study on factors influencing the curative effect of sequential combined interferon and lamivudine therapy in children with immune-tolerant phase chronic hepatitis B]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2019
Zhu SS, Dong Y, Zhang HF, Wang LM, Xu ZQ, Zhang M, Gan Y, Chen DW, Wang FC, Yan JG, Zhao P.   +10 more
europepmc   +1 more source

[Effect of antiviral therapy on the occurrence of hepatitis B-related hepatocellular carcinoma]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2019
Sun J, Zhang S, Wang YX, Zhu L, Xing HC.
europepmc   +1 more source

[Application of HBsAg-positive liver donor in liver transplantation for HBV-related liver disease]. [PDF]

Zhonghua Gan Zang Bing Za Zhi, 2016
Zhang BC, Chen H, Shen ZY, Wang X, Fan TY, Li J, Zhang Q, Chen XG, Xu GX.   +8 more
europepmc   +1 more source