Results 71 to 80 of about 29,985 (230)

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec, Ondrej Simonik, Zuzana Kratka, Lukas Ded, Jana Vondrakova, Maryam Qasemi, Barbora Bryndova, Michala Krejci, Daniela Spevakova, Vishma Pratap Sur, Radomir Kren, Tomas Hradec, Pavel Skrobanek, Ludmila Boublikova, Libor Zamecnik, Tomas Buchler, Jiri Neuzil, Pavla Postlerova, Katerina Komrskova   +18 more
wiley   +1 more source

PTEN is involved in modulation of vasculogenesis in early chick embryos [PDF]

, 2013
Summary PTEN is a tumor suppressor gene that is mutated and/or deleted in many types of tumor. This gene also plays a very distinct role in the early stages of embryonic development such as cell migration, proliferation and migration.
Chuai, Manli, Lee, Kenneth Ka Ho, Li, Yan, Wang, Li Jing, Wang, Xiao Yu, Wu, Ting, Yang, Xuesong   +6 more
core   +3 more sources

In Situ Expression of miR‐371a‐3p and miR‐373‐3p in Testicular Germ Cell Tumours and Detection in Serum

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCTs) are the most common type of tumour diagnosed in young men, and reliable non‐invasive biomarkers are crucial for clinical management. MicroRNAs (miRNAs) from the miR‐371–373 cluster have recently been identified as novel and more sensitive serum biomarkers than the conventional protein‐based ...
Nina Mørup, Merve Tatli, Thomas Wagner, Helle Margit Albrechtsen, Gülizar Saritas, Gedske Daugaard, Sofia B. Winge, Kristian Almstrup   +7 more
wiley   +1 more source

Orbital Yolk Sac Tumor in a 2-Year-Old Female Child Presenting With Proptosis—A Rare Entity

Case Reports in Radiology
Yolk sac tumors are nonseminomatous malignant germ cell tumors that arise from the ovary and testis. Extragonadal disease is rare, with the head and neck representing only 5% of reported cases. Pure orbital yolk sac tumors are extremely uncommon, with no
Hilda Makungu, Morice Ndunguru, Ugumba Kwikima, Frederick R. Lyimo, Trish Scanlan, Alan Beausang, Justin Hendrix, Frank Minja, Sundeep M. Nayak   +8 more
doaj   +1 more source

YOLK SAC TUMOR OVARIUM

Jurnal Radiologi Indonesia, 2020
Yolk sac tumor called endodermal sinus tumor, is a rare and very malignant germ cell tumor. The second largest ovarian germ cell tumor after dysgerminoma, with an incidence of 1% of ovarian malignancies. Tumors usually appear as fast-growing masses in young women.
Lenny Violetta, Indrastuti Normahayu, Bambang Soeprijanto, Galuh Ayu Treswari   +3 more
openaire   +1 more source

Vimentin downregulation is an inherent feature of murine erythropoiesis and occurs independently of lineage [PDF]

, 1990
In mammalian erythropoiesis, the mature cells of the primitive lineage remain nucleated while those of the definitive lineage are anuclear. One of the molecular and structural changes that precedes enucleation in cells of the definitive lineage is the ...
Lazarides, Elias, Sangiorgi, Frank, Woods, Catherine M.   +2 more
core  

Visualising apoptosis in live zebrafish using fluorescence lifetime imaging with optical projection tomography to map FRET biosensor activity in space and time [PDF]

, 2015
Fluorescence lifetime imaging (FLIM) combined with optical projection tomography (OPT) has the potential to map Förster resonant energy transfer (FRET) readouts in space and time in intact transparent or near transparent live organisms such as zebrafish ...
Alexandrov, Y, Andrews, N, Bugeon, L, Dallman, MJ, Frankel, P, French, PMW, Frolov, A, Kelly, DJ, Kerry, L, Kumar, S, Lockwood, N, McGinty, J, Ramel, M-C, Warren, SC   +13 more
core   +2 more sources

Incidence of Gonadal and Extragonadal Germ Cell Tumours in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Klinefelter's syndrome (KS; 47, XXY) is associated with an altered risk profile for malignancies compared with non‐KS males. In particular, several reports have noted a striking association between KS and extragonadal germ cell tumours (EGCTs), especially in the mediastinum, whereas the risk of testicular germ cell tumours (TGCTs ...
Aksh Tailor, Oishee Bandyopadhyay, Nahian Ahmed, Kapishan Shanmugathasan, Alice Cotton, ChingHao Chen, Tet Yap   +6 more
wiley   +1 more source

Deficiency of autotaxin/lysophospholipase D results in head cavity formation in mouse embryos through the LPA receptor-Rho-ROCK pathway [PDF]

, 2010
Autotaxin, encoded by the Enpp2 gene, generates lysophosphatidic acid (LPA) extracellularly, eliciting various cellular responses through specific LPA receptors.
Keino-Masu Kazuko, Koike Seiichi, Masu Masayuki, 桝 和子, 桝 正幸   +4 more
core   +1 more source

Broader Familial Cancer Risk in Relatives of Testicular Cancer Patients: Insights From Two Mediterranean Populations

Andrology, EarlyView.
ABSTRACT Background Familial clustering of testicular germ cell tumour (TGCT) is well‐established, whereas the risk of non‐testicular cancer among relatives remains inconsistent across studies. Objective To evaluate the overall and site‐specific cancer risk among first‐degree relatives and grandparents of TGCT patients compared to cancer‐free controls.
Csilla Krausz, Chiara Abrardo, Viktoria Rosta, Daniel Moreno‐Mendoza, Luca Bressan, Matteo Vannucci, Rebecca Passerotti, Arianna Meacci, Ginevra Farnetani, Viola Bonini, Giovanni Corona, Maria Grazia Fino, Eduard Ruiz‐Castañé, Antoni Riera‐Escamilla   +13 more
wiley   +1 more source