Results 61 to 70 of about 1,321,937 (219)

Ovarian Yolk Sac Tumors: Is Fertility Preservation Possible?

Advanced Biomedical Research
Yolk sac tumors make up 14% to 20% of all malignant ovarian germ cell tumors. Serum alpha-fetoprotein (AFP) levels are elevated in a significant number of patients and are useful for monitoring the response to treatment and for post-treatment ...
Fariba Behnamfar, Maryam Nazemi, Behnoosh Mohamadi   +2 more
doaj   +1 more source

Extragonadal yolk sac tumor outside of the midline of the body: a case report of a child with a yolk sac tumor of the pontocerebellar angle

, 2009
Yolk sac tumor is a rare germ cell neoplasm occurring mainly in the gonads. Extragonadal yolk sac tumor is a very rare malignancy; its main distribution is along the midline of the body at three principal sites: mediastinum, central nervous system and ...
Nadia Puma, Ilaria Lazzareschi, Riccardo Riccardi, Coccia, Paola, Furfaro, Ilaria Francesca Lucina, Ilaria Francesca Furfaro, Paola Coccia, Lazzareschi, Ilaria, Riccardi, Riccardo, Puma, Nadia   +9 more
core   +1 more source

Intracranial yolk sac tumor in an adult patient: MRI, diffusion-weighted imaging and 1H MR spectroscopy features [PDF]

Vojnosanitetski Pregled, 2012
Introduction. Yolk sac tumors represent only 5%-7% of intracranial germ cell tumors, which comprise about 1% of all primary brain tumors in adults. Literature data about nonspecific imaging characteristics of these tumors are scant.
Mačvanski Marija, Ristić-Baloš Dragana, Vasić Brankica, Lavrnić Slobodan, Gavrilović Svetlana, Milićević Mihajlo, Milenković Sanja, Stošić-Opinćal Tatjana   +7 more
doaj   +1 more source

The Yolk Sac Feeds Pancreatic Tumors [PDF]

Immunity, 2017
In this issue of Immunity, Zhu et al. (2017) report that tumor-associated macrophages in a mouse model of pancreatic ductal adenocarcinoma (PDAC) originate from both the yolk sac (YS) and bone marrow. Differential ablation of these populations indicates that only the YS-derived macrophages promote PDAC progression and growth.
openaire   +3 more sources

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

Andrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino, Matteo Lampitto, Alfredo Fusco, Marco Barchi, Francesco Esposito, Paolo Chieffi   +5 more
wiley   +1 more source

Right Ventricular Heart Failure from a Cardiac Yolk Sac Tumor [PDF]

, 2018
A grant from the One-University Open Access Fund at the University of Kansas was used to defray the author's publication fees in this Open Access journal.
Damjanov, Ivan, Aniket S. Rali, Rali, Aniket S., Joel Grigsby, Gupta, Kamal, Nicholas Isom, Kamal Gupta, Ivan Damjanov, Hubbard, Kevin P., Grigsby, Joel, Kevin Hubbard, Isom, Nicholas   +11 more
core   +1 more source

A Unified Machine Learning Model for Relapse Prediction in Clinical Stage I Testicular Cancer

Andrology, EarlyView.
ABSTRACT Background Approximately one‐fourth of patients with clinical stage I testicular cancer relapse. For decades, risk stratification has been based on different tumor characteristics for seminomas and non‐seminomas. Previous studies primarily used Cox proportional‐hazards models and included only a limited number of variables.
Thomas Wagner, Ramtin Zargari Marandi, Jakob Lauritsen, Daniel Dawson Murray, Mikkel Bandak, Birgitte Grønkær Toft, Dan Berney, Gedske Daugaard   +7 more
wiley   +1 more source

TESTİSTE YOLK - SAC TUMOR OLGUSU

Urology Research and Practice, 2019
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A. Öner, E. Öztan, Mete Çek, V. Solok
doaj   +2 more sources

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam, M Figura, J Heyer, S Lieber, M Huber, KL Loveland, HC Schuppe, Daniela Fietz   +7 more
wiley   +1 more source