Results 101 to 110 of about 2,889,165 (371)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

TWILIGHT AND INDONESIAN YOUNG ADULT FICTION TUILET’: A PARODY [PDF]

open access: yes, 2012
This paper examines how Stephanie Meyer’s Twilight is parodied by the Indonesian contemporary young adult Tuilet. By using theory of parody, this paper is expected to provide a critical analysis of the teen novel which have similarities and ...
Pramesti , Tri
core  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

The Importance of Young Adult Provisions in Massachusetts' Health Reform [PDF]

open access: yes, 2010
Analyzes data on the impact of Massachusetts' reform provisions to expand coverage for young adults by raising the eligibility age limit for private dependent coverage and offering "Young Adult Plans" through the insurance ...

core  

Provocation of brachial plexus and systemic symptoms during the elevated arm stress test in individuals with myalgic encephalomyelitis/chronic fatigue syndrome or idiopathic chronic fatigue

open access: yesJournal of Translational Medicine
Background We have noted that some adolescents and young adults with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) report difficulty with arms-overhead activities, suggestive of brachial plexus dysfunction or thoracic outlet syndrome (TOS).
Charles C. Edwards   +9 more
doaj   +1 more source

Three-Dimensional Measures of Bony Resection During Femoral Osteochondroplasty Are Related to Alpha Angle Measures: A Cadaveric Study

open access: yesArthroscopy, Sports Medicine, and Rehabilitation, 2021
Purpose: To determine whether 3-dimensional (3D)–reconstructed proximal femoral bone models can be used to quantify femoral osteochondroplasty and to determine whether the 3D-based metrics are related to clinical alpha angle measures.
Thomas D. Alter, M.S.   +7 more
doaj  

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

Will Teens Go Red? Low Cardiovascular Disease Awareness Among Young Women

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The American Heart Association Go Red for Women campaign has improved awareness of cardiovascular disease (CVD) among adult women aged 25 years and older. Little is known about awareness among younger women.
Holly C. Gooding   +5 more
doaj   +1 more source

Design Implications for a Social and Collaborative Understanding of online Information Assessment Practices, Challenges and Heuristics [PDF]

open access: yes
The broader adoption of social media platforms (e.g., TikTok), combined with recent developments in Generative AI (GAI) technologies has had a transformative effect on many peoples' ability to confidently assess the veracity and meaning of information online. In this paper, building on recent related work that surfaced the social ways that young people
arxiv   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

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