Results 71 to 80 of about 2,889,165 (371)

Development of modularity in the neural activity of children's brains [PDF]

Phys. Biol. 12 (2015) 016009, 2015
We study how modularity of the human brain changes as children develop into adults. Theory suggests that modularity can enhance the response function of a networked system subject to changing external stimuli. Thus, greater cognitive performance might be achieved for more modular neural activity, and modularity might likely increase as children develop.
arxiv   +1 more source

Integrative systems‐level analysis reveals a contextual crosstalk between hypoxia and global metabolism in human breast tumors

Molecular Oncology, EarlyView.
Breast tumor samples scored for metabolic deregulation (M1 to M3) were given a hypoxia score (HS). The highest HS occurred in patients with strongest metabolic deregulation (M3), supporting tumor aggressiveness. HS correlated with the highest number of metabolic pathways in M1. This suggests hypoxia to be an early event in metabolic deregulation.
Raefa Abou Khouzam, Salem Chouaib, Mohammad Askandar Iqbal   +2 more
wiley   +1 more source

Views of young people with chronic conditions on transition from pediatric to adult health services [PDF]

, 2016
PURPOSE: This study sought to identify and describe the views of young people with chronic conditions about the transition from pediatric to adult services. METHODS: Q methodology was used to identify young people’s views on transition.
Blum, Bolton-Maggs, Brown, Cheung, Colver, Cooley, Davies, Dovey-Pearce, Ellingsen, Farre, Farre, Fegran, Gallagher, Jedeloo, Jordan, Kaufman, Kennedy, Kennedy, Ko, Lai, Lugasi, Lyon, Maxwell, McConachie, McDonagh, Richards, Schmolck, Scott, Soanes, Stam, Tielen, Tuchman, Tuffrey, van Staa, Watson, Watts, Wood   +36 more
core   +2 more sources

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Creep Characterization of Inconel 718 Lattice Metamaterials Manufactured by Laser Powder Bed Fusion

Advanced Engineering Materials, EarlyView., 2023
Herein, the creep characteristics of additively manufactured Inconel 718 metamaterials are investigated. The creep behavior of metamaterials and the effects of microstructural defects are assessed, and the microstructure defects are accurately captured using Kachanov's creep damage model.
Akash Singh Bhuwal, Yong Pang, Ian Maskery, Ian Ashcroft, Wei Sun, Tao Liu   +5 more
wiley   +1 more source

Do young people experiencing the transition from children’s services to adult services understand the process and what their choices are? [PDF]

, 2010
This project research examines the understanding that young people who receive services from North Yorkshire Children's Social Care Disabled Children's teams, have of the process of transition to Adult and Community Services.

core  

Vasopressin Prolongs Behavioral and Cardiac Responses to Mild Stress in Young But Not in Aged Rats [PDF]

, 1992
In young male Wistar rats sudden silence superimposed on low intensity background noise evokes a relative decrease in heart rate. This bradycardia is accompanied by immobility behavior.
Bohus, B.,, Buwalda, B.,, Koolhaas, J.M.,, Luiten, P.G.M.,, Nyakas, C.,   +4 more
core   +3 more sources

Building RECOVERY: development of the registry of eating disorders and their co-morbidities OVER time in youth

Journal of Eating Disorders
Background Eating disorder (ED) research is limited by the lack of longitudinal cohort studies, particularly those in adolescents, and the lack of inclusion of multiple perspectives and diagnoses.
Tracy K. Richmond, Emily Farbman Kadish, Monique Santoso, Carly E. Milliren, Meredith Kells, Genevieve Alice Woolverton, Elizabeth R. Woods, Sara F. Forman   +7 more
doaj   +1 more source

Associations between adverse childhood experiences and early adolescent problematic screen use in the United States

BMC Public Health, 2023
Background Problematic screen use, defined as an inability to control use despite private, social, and professional life consequences, is increasingly common among adolescents and can have significant mental and physical health consequences.
Julia H. Raney, Abubakr. A Al-shoaibi, Kyle T. Ganson, Alexander Testa, Dylan B. Jackson, Gurbinder Singh, Omar M. Sajjad, Jason M. Nagata   +7 more
doaj   +1 more source

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source