Results 111 to 120 of about 9,156,647 (313)

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Taurine ameliorates lung injury induced by VOCs inhalation exposure in young rats

open access: yesJournal of Functional Foods
Exposure to volatile organic compounds (VOCs) is associated with an increased risk of lung function impairment and inflammation, particularly in infants and children. However, there is still lack of effective protective methods.
Yongchao Gao   +8 more
doaj   +1 more source

Young Lives Ethiopia: Lessons from longitudinal research with the children of the millennium [PDF]

open access: yes, 2018
This summary is based on the Young Lives Country Report Lessons from Longitudinal Research with the Children of the Millennium, highlighting the context in which this research was conducted, key findings, and implications for policy and practice.
Young Lives, Lives, Young
core  

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Cognitive function and physical performance in young adults who had and had not experienced the COVID-19 infection

open access: yesInternational Journal of Adolescence and Youth
The aim of the present study is to compare the cognitive function and physical performance of young adults who have experienced the COVID-19 infection with those who have not.
Suphannika Ladawan   +3 more
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

open access: yesFEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose   +9 more
wiley   +1 more source

The weakened memory function in young overweight people

open access: yesAdvances in Rehabilitation, 2019
Blanka Dwojaczny   +2 more
doaj   +1 more source

Population-based estimation of renal function in healthy young Indian adults based on body mass index and sex correlating renal volume, serum creatinine, and cystatin C

open access: yesInternational Journal of Nephrology and Renovascular Disease, 2016
Prashanth Rajagopalan,1 Georgi Abraham,2 Yuvaram NV Reddy,2 Ravivarman Lakshmanasami,1 ML Prakash,1 Yogesh NV Reddy2 1Department of General Medicine, Mahatma Gandhi Medical College and Research Institute, Puducherry, 2Department of Nephrology, Madras ...
Rajagopalan P   +5 more
doaj  

Prevalence and family function associated with suicide-related behaviors in vocational college population of southern China: the mediating role of depression

open access: yesFrontiers in Psychiatry
BackgroundSuicide is positively associated with a range of psychological risk factors such as family function and depression. However, it remains unclear if depression mediates the association between family function and suicide in Chinese adolescents ...
He Wang, Yingyu Zhong, Yueyun Wang
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

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