Results 91 to 100 of about 9,156,647 (313)
A strong future for young people leaving out-of-home care [PDF]
, 2014 Young people leaving care or who have left care are over-represented in the statistics on homelessness, early school leaving and contact with the criminal justice system.
Toni Beauchamp
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Frontiers in Public HealthBackgroundThere are limited studies exploring the relationship between physical activity (PA), cognitive function, and the brain processing characteristics in healthy older adults.MethodsA total of 41 participants (42.7 ± 20.5 years, 56.1% males) were ...
Jie Feng +6 more
doaj +1 more source
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Journal of Children's Orthopaedics, 2018 Purpose To describe self-reported life satisfaction and motor function of young adults with cerebral palsy (CP). Methods A total of 57 young adults with spastic CP classified as levels I (seven), II (25), III (16), IV (nine) by the Gross Motor Function ...
N. Lennon, C. Church, F. Miller
doaj +1 more source
How young people are faring 2012 [PDF]
, 2012 This report provides an independent, up-to-date and in-depth analysis of the education, training and work activities of young Australians. The series provides important information on how successfully our education and training system is working to meet
Stephen Lamb, Lyn Robinson
core
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
National Journal of Physiology, Pharmacy and Pharmacology, 2019 Background: Menstrual cycle involves three phases: Menstrual, follicular, and luteal which are regulated by the sex hormones, estrogen and progesterone from the ovary, and also by the gonadotropins leutinizing and follicle-stimulating hormone from the ...
Kaberi De +3 more
doaj +1 more source