Results 81 to 90 of about 9,156,647 (313)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Socioeconomic position in childhood and adult cardiovascular risk factors, vascular structure, and function: cardiovascular risk in Young Finns study [PDF]

, 2005
Objective: To examine the association of childhood socioeconomic position (SEP) with adult cardiovascular risk factors, vascular structure, and vascular function in a contemporary population of young adults. Design: Population based prospective cohort
Keltikangas-Järvinen, L., Kivimäki, M, Ferrie, J E, Keltikangas-Järvinen, L, Raitakari, O.T., Raitakari, O T, Elovainio, M., Viikari, J.S.A., Vahtera, J, Elovainio, M, Juonala, M., Viikari, J S A, Vahtera, J., Leino, M, Pulkki-Råback, L., Smith, Davey G, Davey Smith, G., Ferrie, J.E., Juonala, M, Leino, M., Pulkki-Råback, L, Kivimäki, M.   +21 more
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The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Young Lives survey design and sampling (Round 5): Ethiopia [PDF]

, 2018
This fact sheet describes the survey methods and sample design in Ethiopia and attrition rates throughout 15 years of the study (from Round 1 in 2002 to Round 5 in 2016).
Young Lives, Young Lives, Young
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Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Executive Function and young children's Cardinality Principle: the mediating role of the Approximate Number System and the moderating role of age

Frontiers in Psychology
BackgroundExecutive Function and the Approximate Number System are well-established as critical components in developing the Cardinality Principle in young children.
Huanhuan Li, Huijuan Di, Bingyu Duan, Mengzhen Luo, Yifang Wang, Zhenglu Wang   +5 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

What works with children and young people involved in crime [PDF]

, 2004
This review was commissioned by Audit Scotland in 2002 to examine the evidence on 'what works?' as it applies to children and young people involved in offending in Scotland.
Buist, Maureen, Whyte, Bill
core   +2 more sources

Letter from Joseph Wilbourn Young to Bessie Young, Edna, Alabama, October 6, 1918

, 1918
A soldier in the American Expeditionary Force stationed in Europe during and immediately after World War I writes a letter home in ...
Young, Joseph Wilbourn
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