Results 61 to 70 of about 1,173,328 (266)
PLoS ONE, 2019 ObjectiveTo investigate age-associated changes in airway microbiome composition and their relationships with lung function and arterial stiffness among genetically matched young and elderly pairs.MethodsTwenty-four genetically linked family pairs ...
Shuen Yee Lee +8 more
doaj +1 more source
Anisotropic young diagrams and jack symmetric functions [PDF]
Functional Analysis and Its Applications, 2000 16 pages, AmSTeX, uses EPSF, three EPS ...
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Role of Th17-cell related cytokines in geriatric asthma
Journal of International Medical Research, 2019 Objective This study aimed to investigate the pathogenesis of geriatric asthma through immunoglobulin E (IgE), interleukin-17A (IL-17A), IL-17F, and glucocorticoid receptor-β (GR-β) expression.
Zhang Quan-san +3 more
doaj +1 more source
Upper Functional Gastrointestinal Disorders in Young Adults
Medical Archives, 2012 Functional Gastrointestinal disorders (FGID) are common disorders in gastroenterology which are common in young adults. The aim of this study is evaluating the prevalence of upper FGID in iranian young adults.This was a cross-sectional study which was on 995 persons who were going to marry.
Peyman, Adibi +3 more
openaire +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Endothelial function in young men with essential hypertension
Российский кардиологический журнал, 2004 The aim of the study was to evaluate the association between markers of endothelial function and arterial hypertension (AH). We measured the plasma level of nitrite and nitrate and flow-mediated vasodilatation of the brachial artery (endothelium ...
G. R. Yanovskaya +2 more
doaj
Lung Function in Young Adults and Risk of Cardiovascular Events Over 29 Years: The CARDIA Study
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Diminished peak lung function in young adulthood is a risk factor for future chronic obstructive pulmonary disease. The association between lung disease and cardiovascular disease later in life is well documented.
Michael J. Cuttica +12 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source