Results 91 to 100 of about 4,030,490 (290)

Simulating young star clusters with primordial binaries

, 2004
8 pages, to be published in the proceedings of the conference on Massive Stars In Interacting Binaries in Canada, 16-20 August 2004 (eds. N. St-Louis and A. Moffat)
Portegies Zwart, S.F., McMillan, S.L.W.
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Identification of Star Clusters in M31 from PAndAS Images Based on Deep Learning

The Astrophysical Journal Supplement Series
The identification of star clusters holds significant importance in studying galaxy formation and evolution history. However, the task of swiftly and accurately identifying star clusters from vast amounts of photometric images presents an immense ...
Baisong Zhang, Bingqiu Chen, Haibo Yuan, Pinjian Chen, Shoucheng Wang, Lunwei Zhang, Yi Ren, Helong Guo   +7 more
doaj   +1 more source

Micro-tidal disruption events in young star clusters

Astronomy & Astrophysics
Context. Dense young star clusters (YSCs) are ideal environments for dynamical interactions between stars and stellar compact objects, such as black holes and neutron stars.
Rastello Sara, Iorio Giuliano, Gieles Mark, Wang Long   +3 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Between the Cosmic-Ray “Knee” and the “Ankle”: Contribution from Star Clusters

The Astrophysical Journal
We show that massive, young star clusters may be possible candidates that can accelerate Galactic cosmic rays (CRs) in the range of 10 ^7 –10 ^9 GeV (between the “knee” and “ankle”).
Sourav Bhadra, Satyendra Thoudam, Biman B Nath, Prateek Sharma   +3 more
doaj   +1 more source

Centrally concentrated star formation in young clusters

Astronomy & Astrophysics
The study of star cluster evolution necessitates modeling how their density profiles develop from their natal gas distribution. Observational evidence indicates that many star clusters follow a Plummer-like density profile.
Assilkhan Adilkhan, Mac Low Mordecai-Mark, Polak Brooke, Abdikamalov Ernazar, Cournoyer-Cloutier Claude, Lewis Sean C., Kalambay Mukhagali, Otebay Aigerim, Shukirgaliyev Bekdaulet   +8 more
doaj   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Using Rapid Rotators as Tracers of Multiplicity Statistics as a Function of Stellar Density

The Astrophysical Journal
Recent works have identified that rapidly rotating stars are predominantly binaries with separations of a few to a few tenths of an astronomical unit. This is a crucial range of separation that is often inaccessible to searches of binary stars, providing
Priyanka Cingirikonda, Marina Kounkel, Joseph Mullen   +2 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source