Results 111 to 120 of about 170,841 (292)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Dynamical evolution of stellar clusters
, 2011 The evolution of star clusters is determined by several internal and external processes. Here we focus on two dominant internal effects, namely energy exchange between stars through close encounters (two-body relaxation) and mass-loss of the member stars
Gieles, Mark
core
How Universal are the Young Cluster Sequences? - the Cases of LMC, SMC, M83 and the Antennae
, 2009 Aims.Recently a new analysis of cluster observations in the Milky Way found evidence that clustered star formation may work under tight constraints with respect to cluster size and density, implying the presence of just two sequences of young massive ...
A. Eckart +22 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective We developed a novel electronic health record sidecar application to visualize key rheumatoid arthritis (RA) outcomes, including disease activity, physical function, and pain, via a patient‐facing graphical interface designed for use during outpatient visits (“RA PRO dashboard”).
Gabriela Schmajuk +16 more
wiley +1 more source
Gamma ray emission from embedded young massive star clusters unveiled by Fermi-LAT [PDF]
EPJ Web of ConferencesMassive star clusters (SCs) have been proposed as additional contributors to Galactic Cosmic rays (CRs), to overcome the limitations of supernova remnants (SNR) to reach the highest energy end of the Galactic CR spectrum.
Peron Giada +3 more
doaj +1 more source
Young star clusters in circumnuclear starburst rings
, 2016 We analyse the cluster luminosity functions (CLFs) of the youngest star clusters in three galaxies exhibiting prominent circumnuclear starburst rings. We focus specifically on NGC 1512 and NGC 6951, for which we have access to H$\alpha$ data that allow ...
Anders, Peter +4 more
core +2 more sources
Neighborhood Socioeconomic Status and Short‐Term Functional Outcomes in Systemic Lupus Erythematosus
Arthritis Care &Research, EarlyView.Objective Individuals with systemic lupus erythematosus (SLE) can accumulate functional status (FS) impairment. We evaluated the association between neighborhood socioeconomic disadvantage, as measured by the Area Deprivation Index (ADI), and FS in a national SLE sample.
Baljeet Rai +7 more
wiley +1 more source
Arthritis Care &Research, Accepted Article.Objective The objective of this article is to identify perceptions of SLE patients regarding artificial intelligence (AI)‐based online symptom assessment tools, and the potential of these tools to address diagnostic barriers. Methods Adults from our SLE research cohort were invited to participate in 60‐90 minute virtual focus groups concerning their ...
Olivia A. Stein +7 more
wiley +1 more source
Additive Gaussian Process Regression for Predictive Design of High‐Performance, Printable Silicones
Advanced Engineering Materials, EarlyView.A chemistry‐aware design framework for tuning printable polydimethylsiloxane (PDMS) for vat photopolymerization (VPP) is developed using additive Gaussian process (GP) modeling. Polymer network mechanics informs variable groupings, feasible formulation constraints, and interaction variables.
Roxana Carbonell +3 more
wiley +1 more source
The Star Cluster System of the NGC 7673 Starburst
, 2002 We investigate the star cluster system in the starburst galaxy NGC 7673 using archival Hubble Space Telescope WFPC2 broad-band images. For the first time we are able to examine the internal structures of the prominent optical clumps in this galaxy.
A. Pasquali +76 more
core +2 more sources