Results 41 to 50 of about 169,580 (246)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Young massive star clusters in M51 [PDF]
Monthly Notices of the Royal Astronomical Society, 2002 A search for young massive star clusters (YMCs) in the nearby face-on spiral galaxy M51 (NGC 5194) has been carried out using UBV CCD images from the prime focus camera on the Lick 3 meter Shane telescope. The YMC population is found to be quite rich with a specific U-band luminosity T_L(U) = 1.4, consistent with the high current star formation rate of
openaire +3 more sources
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
How can young massive clusters reach their present-day sizes?
, 2015 The classic question that how young massive star clusters attain their shapes and sizes, as we find them today, remains to be a challenge. Both observational and computational studies of star-forming massive molecular gas clouds infer that massive ...
Banerjee, Sambaran, Kroupa, Pavel
core +1 more source
Sustainable bioplastics manufacturing from renewable sources
FEBS Open Bio, EarlyView.Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
C32: A Young Star Cluster in IC 1613
Publications of the Astronomical Society of the Pacific, 2000 This paper was harvested from ArXiv.org and ArXiv identifier is arXiv ...
Wyder, Ted K. +2 more
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Multiple stellar populations in Magellanic Cloud clusters. III. The first evidence of an extended main sequence turn-off in a young cluster: NGC1856 [PDF]
, 2015 Recent studies have shown that the extended main-sequence turn off (eMSTO) is a common feature of intermediate-age star clusters in the Magellanic Clouds (MCs).
Aparicio, A. +9 more
core +2 more sources
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Aging and Cancer, EarlyView.Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Massive stars in young VVV clusters [PDF]
Proceedings of the International Astronomical Union, 2016 The role of massive stars in the Galactic evolution is crucial. During their lifetime these stars change the kinematics around them through stellar winds, affect the formation of new stars, ionise and chemically enrich the media with the final supernova explosion. But the census of both massive stars and their host clusters is still poor.
S. Ramírez Alegría +2 more
openaire +1 more source