Results 51 to 60 of about 19,727 (296)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Massive Star Cluster Formation with Binaries. I. Evolution of Binary Populations

The Astrophysical Journal
We study the evolution of populations of binary stars within massive cluster-forming regions. We simulate the formation of young massive star clusters within giant molecular clouds with masses ranging from 2 × 10 ^4 to 3.2 × 10 ^5 M _⊙ .
Claude Cournoyer-Cloutier, Alison Sills, William E. Harris, Brooke Polak, Steven Rieder, Eric P. Andersson, Sabrina M. Appel, Mordecai-Mark Mac Low, Stephen McMillan, Simon Portegies Zwart   +9 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The Impact of Stellar Radiative Feedback on Formation of Young Massive Clusters via Fast H i Gas Collisions

The Astrophysical Journal
Young massive clusters (YMCs) are dense aggregates of young stars and are often speculated as potential precursors to globular clusters. However, the formation mechanism of massive and compact gas clumps that precede YMCs remains unknown.
Ryunosuke Maeda, Tsuyoshi Inoue, Kazuyuki Omukai, Yasuo Fukui, Kisetsu Tsuge   +4 more
doaj   +1 more source

The Evolution of Young Star Clusters In Merging Galaxies [PDF]

Symposium - International Astronomical Union, 1999
The formation of young star clusters in merging galaxies is, by now, well established. The new challenge is to use these young clusters as a tool to address some of the outstanding questions. For example, what fraction of these young clusters become globular clusters? Is this enough to explain the difference in the specific globular cluster frequencies
openaire   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

VLA 22 GHz Imaging of Massive Star Formation in Local Wolf–Rayet Galaxies

The Astrophysical Journal
We present 22 GHz imaging of regions of massive star formation within the Local Wolf–Rayet Galaxy Sample, a NSF Karl G. Jansky Very Large Array survey of 30 local galaxies showing spectral features of Wolf–Rayet (WR) stars.
Nicholas G. Ferraro, Jean L. Turner, Sara C. Beck, Edwin Alexani, Runa Indrei, Bethany M. Welch, Tunhui Xie   +6 more
doaj   +1 more source

Understanding the Planetary Formation and Evolution in Star Clusters (UPiC). I. Evidence of Hot Giant Exoplanets Formation Timescales

The Astronomical Journal, 2023
Planets in young star clusters could shed light on planet formation and evolution since star clusters can provide accurate age estimation. However, the number of transiting planets detected in clusters was only ∼30, too small for statistical analysis ...
Yuan-Zhe Dai, Hui-Gen Liu, Jia-Yi Yang, Ji-Lin Zhou   +3 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Unlocking star formation and evolution mysteries: Insights from young open clusters [PDF]

, 2023
Young star clusters are exceptional laboratories for advancing our understanding of stellar evolution. With the majority of massive stars being born in binary systems, where their properties can be altered significantly through interactions, multiple ...
Wang,Chen
core   +1 more source