Results 61 to 70 of about 6,154 (302)

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Investigating the Nested Structure of the Outflow from the Low Luminosity Protostar IRAS 16253-2429 Using JWST and ALMA

The Astrophysical Journal
Understanding the earliest stage of star and planet formation requires detailed observations to address the connection and interplay between the accretion, outflow, and disk evolution.
Mayank Narang, Himanshu Tyagi, Nagayoshi Ohashi, P. Manoj, S. Thomas Megeath, John J. Tobin, Ewine F. Van Dishoeck, Neal J. Evans II, Dan M. Watson, Alessio Caratti o Garatti, Jes K. Jørgensen, Robert Gutermuth, Yusuke Aso, Henrik Beuther, Leslie W. Looney, David A. Neufeld, Guillem Anglada, Mayra Osorio, Adam E. Rubinstein, Samuel Federman, Lee W. Hartmann, Pooneh Nazari, Nicole Karnath, Hendrik Linz, Thomas Stanke, Tyler L. Bourke, Yao-Lun Yang, Rolf Kuiper, Joel Green, Pamela Klaassen, Wafa Zakri, Nolan Habel, Nashanty Brunken, James Muzerolle, Katerina Slavicinska, Amelia M. Stutz, Lukasz Tychoniec, Scott Wolk, Will R. M. Rocha, William J. Fischer   +39 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

An Embedded Disk (eDisk) in the IceAge: Investigating the Jet and Outflow from Ced 110 IRS4

The Astronomical Journal
We present a comprehensive study of the large-scale structure, jet and outflow morphology, and kinematics of the Class 0/I protostellar binary Ced 110 IRS4, using JWST NIRCam (F150W and F410M) and MIRI MRS observations from the JWST ERC program IceAge ...
Mayank Narang, Nagayoshi Ohashi, John J. Tobin, M. K. McClure, Jes K. Jørgensen, Jinshi Sai (Insa Choi), eDisk + IceAge Team   +6 more
doaj   +1 more source

Millimeter observations of Young Stellar Objects with the CARMA interferometer [PDF]

, 2016
Presento uno studio di 81 young stellar Objects di classe con l'obiettivo di ricavarne la massa in polvere dai ...
Zennaro, Marco
core  

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

The CO Outflow Components Ejected by a Recent Accretion Event in B335

The Astrophysical Journal
Protostellar outflows often present a knotty appearance, providing evidence of sporadic accretion in stellar mass growth. To understand the direct relation between mass accretion and ejection, we analyze the contemporaneous accretion activity and ...
Chul-Hwan Kim, Jeong-Eun Lee, Carlos Contreras Peña, Doug Johnstone, Gregory J. Herczeg, John J. Tobin, Neal J. Evans II   +6 more
doaj   +1 more source

Accretion bursts of massive young stellar objects and exoplanets [PDF]

, 2022
It has been shown that the mass of a clump accreted during an outburst in the massive young stellar object G358.93-0.03, detected during the monitoring of methanol maser emission and subsequent observations in the far infrared, corresponds to the mass of
Соболев, А. М., Sobolev, A. M.
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

EPISODE. III. The Nested Jet/Outflow Morphology of EC 53 Revealed by JWST and ALMA

The Astrophysical Journal
We present an extensive study of the structure and kinematics of the jet and outflow of EC 53, a Class I protostar with a quasiperiodic variability, using combined James Webb Space Telescope (JWST) and Atacama Large Millimeter/submillimeter Array (ALMA ...
Seonjae Lee, Jeong-Eun Lee, Chul-Hwan Kim, Seokho Lee, Doug Johnstone, Gregory J. Herczeg, Joel Green, Logan Francis, Yao-Lun Yang, Hyundong Lee, Nagayoshi Ohashi   +10 more
doaj   +1 more source