Results 131 to 140 of about 16,224,136 (409)

Strategies to Strengthen Youth Leadership and Youth Participation Opportunities in Central Appalachia [PDF]

open access: yes, 2015
The purpose of this study was to assess opportunities for strengthening youth leadership and participation in the Central Appalachian region. In particular, authors Rebecca O’Doherty, Ada Smith, Ben Spangler, Elandria Williams, and Katie Richards ...
O\u27Doherty, Rebecca   +4 more
core   +1 more source

Near‐Infrared‐Driven Metal–Organic Frameworks‐Based Nanorobots for Controlled Photothermal‐Chemical Therapy Synergistic Induction of Cancer Cell Death

open access: yesAdvanced Robotics Research, EarlyView.
To achieve efficient cancer cell death, a bowl‐shaped PDA@UiO‐66@DOX nanorobot drug‐delivery nanoplatform was developed. Near‐infrared irradiation not only drives the nanorobot to exhibit self‐thermophoretic motion and elevates temperature but also triggers Doxorubicin (DOX) release via hyperthermia, enhancing cancer cells uptake of DOX and thereby ...
Tong Lin   +6 more
wiley   +1 more source

Unleashing Youth Potential: Understanding and Growing Youth Participation in Philanthropy and Volunteerism [PDF]

open access: yes, 2004
This paper attempts to situate youth in philanthropy in the context of the organizational culture and practices of Canadian community foundations.
Barbara Oates
core  

ST6GAL1‐Mediated Sialylation Stabilizes PD‐L1 and Drives Immunosuppressive Tumor Microenvironment in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
ST6GAL1 plays a critical role in tumor progression and immune regulation in colorectal cancer (CRC). Its depletion significantly suppresses the malignant phenotype of CRC cells and enhances the efficacy of anti‐PD‐L1 therapy. High ST6GAL1 expression promotes an immune‐activated tumor microenvironment (TME), characterized by increased infiltration of ...
Ximo Xu   +15 more
wiley   +1 more source

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

open access: yesAdvanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian   +26 more
wiley   +1 more source

The effects of various retention factors on the choice of where rural origin Umthombo Youth Development Foundation health science graduates work

open access: yesRural and Remote Health
Introduction: South Africa has an inequitable distribution of health workers between the public and private sector, with rural areas being historically underserved. As rural background of health workers has been advocated as the strongest predictor of
Richard Gavin MacGregor, Andrew Ross
doaj   +1 more source

Fabricating 2D MoS2 with Edge Sulfur Vacancy Defects by Heavy Ion Bombardment Shear‐Exfoliation for Enhanced Sodium Storage

open access: yesAdvanced Science, EarlyView.
Few‐layered MoS2 with edge sulfur vacancies (L‐MoS2‐x) was prepared via heavy ion bombardment shear‐exfoliation. This anode demonstrates superior sodium storage performance, delivering 399.91 mAh g−1 at 5 A g−1 and maintaining 460.71 mAh g−1 at 1 A g−1 after 100 cycles in sodium‐ion batteries (SIBs). Abstract Vacancy engineering is widely considered an
Feiyan Mu   +7 more
wiley   +1 more source

A collaborative approach to improving youth mental health. [PDF]

open access: yes, 2003
Nga Taiohi Whai Marama / Youth Connex was developed collaboratively by three organisations: Health Waikato Mental Health, Te Runanga o Kirikiriroa, and Linkage.
Goodwin, Debbie Waireka Tuhi
core   +1 more source

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