Results 71 to 80 of about 373,181 (317)

2018 Report on the NEO Initiative [PDF]

open access: yes, 2019
380,000 is the number of lives transformed by the New Employment Opportunities (NEO) Initiative, during 2013-2018 period. In a region plagued by precarious rates of youth unemployment, NEO has succeeded in closing the skills gap of vulnerable youth and ...
Inter-American Development Bank
core   +1 more source

Targeting UXS1‐Dependent Glucuronate Detoxification Potentiates Metformin's Anti‐Tumor Efficacy in Lung Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
This study reveals that metformin promotes glucuronic acid metabolism in lung adenocarcinoma by activating UGDH S476 phosphorylation and enhancing the conversion of UDPG to UDPGA based on metabolomics analysis. Through compound virtual screening, it is found that plantainoside targeting UGDH downstream UXS1 leads to UDPGA toxicity accumulation ...
Qihai Sui   +14 more
wiley   +1 more source

Annual report of the Texas Youth Council to the governor, fiscal year ended August 31 ...

open access: yes, 1951
Annual report of the Texas State Youth Development Council describing goals, activities, and accomplishments during fiscal year ...
Texas. State Youth Development Council.
core  

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

open access: yesAdvanced Science, EarlyView.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu   +15 more
wiley   +1 more source

Annual report of the Texas Youth Council to the governor, fiscal year ended August 31 ...

open access: yes, 1952
Annual report of the Texas State Youth Development Council describing goals, activities, and accomplishments during fiscal year ...
Texas. State Youth Development Council.
core  

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

open access: yesAdvanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao   +11 more
wiley   +1 more source

Annual report of the Texas Youth Council to the governor, fiscal year ended August 31 ...

open access: yes, 1957
Annual report of the Texas State Youth Development Council describing goals, activities, and accomplishments during fiscal year ...
Texas. State Youth Development Council.
core  

RNA Helicase DDX21 Controls CD4+ T Cell Proliferation and Promotes Inflammatory Bowel Disease via Translational Control

open access: yesAdvanced Science, EarlyView.
ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang   +11 more
wiley   +1 more source

Annual report of the Texas Youth Council to the governor, fiscal year ended August 31 ...

open access: yes, 1955
Annual report of the Texas State Youth Development Council describing goals, activities, and accomplishments during fiscal year ...
Texas. State Youth Development Council.
core  

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

open access: yesAdvanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu   +18 more
wiley   +1 more source

Home - About - Disclaimer - Privacy