Results 161 to 170 of about 1,029,947 (295)

Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7

Advanced Science, EarlyView.
Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim, Gaeun Lee, Saemin An, Hanseul Park, Hongwon Kim, Jisung Kim, Soi Kang, Sumin Kim, Daeyeol Kwon, Jeonghyun Park, Yerim Hwang, Seonghun Kim, Xiuwen Yuan, Jaehoon Jeong, Hamin Lee, Hui Kwon Kim, Jongpil Kim   +16 more
wiley   +1 more source

Xiang zhu Sui yuan nü di zi shi xuan

, 1929
袁枚選 ; 增註者謝璿].Yuan Mei xuan ; zeng zhu zhe Xie Xuan]

core  

Correction: Integrative bioinformatics and in vivo validation suggest a potential role of <i>Cbr4</i> in alcohol use disorder through modulation of lipid metabolism and treg cell function in the central amygdala. [PDF]

Front Genet
Ge Y, Yuan Y, Li M, Huang Z, Zhang C, Yu C, Xu J, Zhang S, Guo H, Zhang X, Fu R, Ren Z.   +11 more
europepmc   +1 more source

A Sustainable Bio‐Based Epoxy Thermoset as a High‐Performance Alternative to BPA‐Based Resins

Advanced Science, EarlyView.
A rigid–flexible bio‐based epoxy network integrates soybean oil, lignin, and maleic anhydride to overcome the strength–toughness–sustainability trade‐off of conventional BPA epoxy. The thermoset delivers excellent performance as both a structural adhesive and a matrix for glass‐fabric composites, while enabling pH‐responsive degradation, environmental ...
Jiyun Qi, Xinyi Hui, Xipeng Zhang, Jia‐Long Wen, Tong‐Qi Yuan   +4 more
wiley   +1 more source

Implicit Health Beliefs and Suicidal Ideation in Chinese College Students: The Serial Mediating Roles of Lifestyle Behaviors and Anxiety Symptoms. [PDF]

Behav Sci (Basel)
Lai X, Huang J, Yan H, Shi Z, Zhang Y, Yang Y, Liu X.   +6 more
europepmc   +1 more source

From Displacement to Angle: Diamond‐Based 3D Rotation Sensing for High‐Precision Cellular Force Measurement

Advanced Science, EarlyView.
Cellular forces are traditionally inferred from displacement measurements, which lack rotational information and are constrained by linear model assumptions. This work replaces displacement with rotational angle for the fundamental mechanical readout.
Linjie Ma, Bicong Wang, Tai Nam Yip, Jiahua Zhang, Yicheng Wang, Luyao Zhang, Yong Hou, Yuan Lin, Zhiqin Chu   +8 more
wiley   +1 more source

Dong hua yi yuan zheng xin lu

, 1912
壬子[192-]Ren zi[192-

core  

Correction: The impact of short-term intensive fasting on physical health and gut microbiota in obese individuals. [PDF]

Front Nutr
Ji F, Wang S, Wang L, Zhao Y, Zhong J, Wang R, Qu J, Lu Y, Yuan N, Zhang Q.   +9 more
europepmc   +1 more source

UCtracker: A Deep Learning–Based DNA Methylation Model for Noninvasive Diagnosis and Recurrence Surveillance of Urothelial Carcinoma in a Prospective Study

Advanced Science, EarlyView.
We developed UCtracker, a urine DNA methylation–based deep learning model, for noninvasive diagnosis and postoperative surveillance of urothelial carcinoma. UCtracker demonstrates high diagnostic accuracy, robustness at ultralow sequencing depth, early recurrence detection, and dynamic risk‐stratified monitoring of molecular residual disease ...
Shengwei Xiong, Gaojie Li, Yucai Wu, Yuan Liang, Heng Guo, Yu Zhang, Gengyan Xiong, Long Tian, Xin Zhang, Ye Tian, Zhengguo Ji, Bin Guo, Yue Shi, Jian Fan, Zhihua Li, Yanqing Gong, Shiming He, Xuesong Li, Weimin Ci, Liqun Zhou   +19 more
wiley   +1 more source

Prevalence and Factors Associated With Financial Toxicity in Cervical Cancer Patients: A Cross-Sectional Study. [PDF]

Nurs Open
Li D, Wen M, Zhao Y, Nie T, Li M, Yuan L, Wang M, Zhu X, Li Y, Zhang Q, He C.   +10 more
europepmc   +1 more source