Results 171 to 180 of about 1,029,947 (295)

Aberrant GRP78 Phase Transition Sustains Endothelial IRE1α Signaling and Drives Blood–Brain Barrier Failure in Cerebral Amyloid Angiopathy

open access: yesAdvanced Science, EarlyView.
Vascular Aβ40 corrupts GRP78 phase behavior in brain endothelial cells, sustaining IRE1α–TRAF2–JNK signaling and driving apoptosis, tight junction loss, and blood–brain barrier failure in cerebral amyloid angiopathy. Pharmacological IRE1α inhibition restores vascular integrity, reduces leakage, and improves functional outcomes, revealing a targetable ...
Honglin Zheng   +19 more
wiley   +1 more source

Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo

open access: yesAdvanced Science, EarlyView.
By synergistically integrating the long‐distance manipulation fiber probe (LDMFP) and endogenous red blood cells (RBCs) as biocompatible optical elements, a natural RBC biotweezer was developed for the desired microparticle manipulation and immune cell activation within living vasculature, which might offer an alternative tool for intravital optical ...
Tong Yang   +9 more
wiley   +1 more source

Jiang xue yuan de yi ben cao

open access: yes
V.1. 條目 -- 絳雪園得宜本草 / 王晉三集 ; 吳蒙校 -- 絳雪園古方選註 : 六門 : 和劑四十四方 / 王子接註 ; 葉桂校 -- v.2. 絳雪園古方選註 : 寒劑十方 / 王子接註 ; 薛雪校 -- 温劑十九方 / 王子接註 ; 葉桂校 -- 汗劑十三方 / 王子接註 ; 葉桂校 -- 吐劑五方 / 王子接註 ; 王士琳校 -- 下劑二十二方 / 王子接註 ; 葉桂校 -- v.3-4. 絳雪園古方選註 : 內科 / 王子接註 ; 葉桂校 -- v.5. 絳雪園古方選註 : 內科丸方 /

core  

Correction: Predicting Kawasaki disease shock syndrome in children. [PDF]

open access: yesFront Immunol
Zhao Z   +5 more
europepmc   +1 more source

Metal‐Half‐Salen Chemistry for One‐Pot Mineralization on Hydrophobic Polymer Membranes

open access: yesAdvanced Science, EarlyView.
Here we report a versatile one‐pot synthetic strategy for organic–inorganic composite membranes, which leverages a metal half‐Salen system to precisely govern the competing kinetics of coordination and hydrolysis. In contrast to conventional two‐step metal‐phenol chemistries, our integrated approach substantially simplifies the fabrication process ...
Rou‐Ming Wen   +8 more
wiley   +1 more source

Correction to: Integrative multi-omics analysis identifies C-type lectin CNVs as functional targets for breeding mastitis-resistant dairy goats. [PDF]

open access: yesAnim Microbiome
Yuan Y   +15 more
europepmc   +1 more source

Breaking the Kinetics–Loading Trade‐Off in Zinc‐Ion Hybrid Capacitors Through Synergistic Electron–Ion Transport Design

open access: yesAdvanced Science, EarlyView.
High‐mass‐loading carbon cathodes are essential for practical zinc‐ion hybrid capacitors but suffer from severe transport limitations. By combining low‐tortuosity freeze‐dried pore channels with carbon nanotube conductive networks, simultaneous optimization of ion and electron transport is achieved, enabling high‐rate, long‐life pouch cells and ...
Jiacheng Wu   +8 more
wiley   +1 more source

Miro1 Protects Against Acute Kidney Injury Through Modulating Mitochondrial Homeostasis via Interaction With Sirt6

open access: yesAdvanced Science, EarlyView.
Ischemia‐reperfusion reduces Sirt6 activity, thereby increasing Miro1 acetylation. Hyperacetylated Miro1 exhibits perinuclear distribution and degradation, thereby inducing mitochondrial dysfunction and promoting apoptosis in renal tubular epithelial cells. This pathway reveals a mechanistic link between Sirt6‐mediated deacetylation and Miro1 stability
Lin Wu   +12 more
wiley   +1 more source

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