Results 261 to 270 of about 2,164,210 (341)

Selective Interfacial Barriers Drive High‐Performance GeTe Thermoelectrics

open access: yesAdvanced Science, EarlyView.
Carrier‐phonon decoupling is the key to developing high‐performance thermoelectric materials. Here, we demonstrate that selective interfacial barriers can decouple carrier and phonon transport, thus achieving an exceptional peak ZT of ∼2.7 at 773 K, along with a record‐high average ZT of 1.9 across 300–773 K in the (Ge0.82Mn0.04Bi0.04Pb0.1Te)0.99(VSe2 ...
Liang‐Cao Yin   +12 more
wiley   +1 more source

Correction: Promotion of stem cell-like phenotype of lung adenocarcinoma by FAM83A via stabilization of ErbB2. [PDF]

open access: yesCell Death Dis
Yuan Y   +8 more
europepmc   +1 more source

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang   +10 more
wiley   +1 more source

T Cell‐Independent Role of PD‐L1 in Kidney Repair: Mitigation of Tubular DNA Damage via PD‐L1/BRCA1 Interaction Following AKI

open access: yesAdvanced Science, EarlyView.
PD‐L1 is primarily expressed in renal tubules and upregulated in both murine models of AKI and renal biopsy samples from patients with AKI. PD‐L1 can promote adaptive TECs repair through interacting with BRCA1, independent of its canonical immunomodulatory function of T cells, and PD‐L1 supplementation may represent a promising therapeutic strategy for
Wei Jiang   +17 more
wiley   +1 more source

Caveolin‐1 Stabilizes SERCA2 to Counteract Acute Kidney Injury via Suppression of Ca2+‐Dependent Endoplasmic Reticulum Stress in Distal Tubules

open access: yesAdvanced Science, EarlyView.
In AKI, initial kidney injury upregulates the expression of Cav‐1, which subsequently binds to and stabilizes SERCA2 via its scaffolding domain and through deubiquitination, thereby regulating Ca2+ homeostasis and ER stress. Conversely, Cav‐1 deficiency accelerates SERCA2 degradation, triggering Ca2+ overload and ER stress, and ultimately exacerbating ...
Yan Zhang   +19 more
wiley   +1 more source

Impact of the Population Medicine Multimorbidity Intervention in Xishui County (POPMIX) on People at High Risk for Chronic Obstructive Pulmonary Disease Who Experience Mental Health Symptoms: Protocol for the POPMIX-MH Cluster Randomized Controlled Trial. [PDF]

open access: yesJMIR Res Protoc
Liu Y   +26 more
europepmc   +1 more source

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