Results 111 to 120 of about 3,851,324 (263)

Analiza kalibracji wyników sondowań CPT z próbnymi odwiertami kolumn przemieszczeniowych CMC

open access: yesPrzegląd Naukowy Inżynieria i Kształtowanie Środowiska, 2018
Kalibracja sondowań CPT z próbnymi odwiertami kolumn CMC (ang. controlled modulus columns) ma w Polsce szerokie zastosowanie w geotechnice ze względu na występujące analogie parametrów wiercenia maszyn wiertniczych do tego rodzaju badań geotechnicznych ...
Karolina Kobrzyńska   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Changes in Kinematic and Spatiotemporal Gait Parameters With a Biarticular Lower Limb Exosuit for Adolescents With Crouch Gait During Level Walking and Stair Climbing

open access: yesIEEE Transactions on Neural Systems and Rehabilitation Engineering
Crouch gait is a prevalent walking abnormality among children with cerebral palsy, characterized by excessive knee and hip flexion during walking. This condition often limits children’s engagement in physical activities and daily life.
Chiara Basla   +4 more
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Unikatowe znalezisko przyborów kupieckich z Jaryszek. Przyczynek do studiów nad rolą peryferycznego otoczenia Poznania we wczesnym średniowieczu

open access: yesSlavia Antiqua
During research at an early medieval site located 11 km away from Poznań’s Ostrów Tumski (Cathedral Island), a set of tools for weighing bullion was found, consisting of balance scales, 10 standardised weights, and a decorative copper alloy necklace ...
Kamilla Waszczuk   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Ultra-Lightweight Collaborative SLAM for Robot Swarms

open access: yesIEEE Access
A key requirement in robotics is the ability to simultaneously self-localize and map a previously unknown environment, relying primarily on onboard sensing and computation.
Vlad Niculescu   +3 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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