Results 131 to 140 of about 373,753 (331)
RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication
Advanced Science, EarlyView.Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song +11 more
wiley +1 more source
Generating neurons in the embryonic and adult brain: compared principles and mechanisms
Comptes Rendus BiologiesNeurogenesis is a lifelong process, generating neurons in the right amount, time and place and with the correct identity to permit the growth, function, plasticity and repair of the nervous system, notably the brain.
Chouly, Mathilde, Bally-Cuif, Laure
doaj +1 more source
Osteoclast‐Derived SLIT3 Mediates Osteoarthritis Pain and Degenerative Changes
Advanced Science, EarlyView.In TMJ‐OA, osteoclasts play a significant role in promoting the growth of sensory nerves at the osteochondral interface. In early OA, TRAP+ osteoclast‐derived SLIT3 induces sensory nerve growth into the condylar cartilage. This nerve growth facilitates the development of pain associated with OA.
Weiwei Zhu +13 more
wiley +1 more source
Advanced Science, EarlyView.Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang +6 more
wiley +1 more source
TnP as a Multifaceted Therapeutic Peptide with System-Wide Regulatory Capacity
PharmaceuticalsBackground: The candidate therapeutic peptide TnP demonstrates broad, system-level regulatory capacity, revealed through integrated network analysis from transcriptomic data in zebrafish.
Geonildo Rodrigo Disner +3 more
doaj +1 more source
Advanced Science, EarlyView.SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He +5 more
wiley +1 more source
Histological Assessment of Intestinal Changes Induced by Liquid Whey-Enriched Diets in Pigs
Veterinary SciencesLiquid whey (LW) is a nutrient-rich dairy by-product and a promising resource for animal nutrition. However, data regarding its impact on intestinal morphology and endocrine signaling are limited.
Kamel Mhalhel +10 more
doaj +1 more source
Four twist genes in zebrafish, four expression patterns [PDF]
, 2007 Igal Germanguz +4 more
openalex +1 more source